×
Aktivieren Sie Javascript in Ihrem Browser, um unsere Webseite optimal zu nutzen.
CDK5R1 Antikörper
CDK5R1
Reaktivität: Human, Maus, Ratte
WB, IF, IHC (p)
Wirt: Kaninchen
Polyclonal
unconjugated
Produktdetails anti-CDK5R1 Antikörper
(ausblenden)
Target
Alle CDK5R1 Antikörper anzeigen
CDK5R1
(Cyclin-Dependent Kinase 5, Regulatory Subunit 1 (p35) (CDK5R1))
Reaktivität
Alle Reaktivitäten für CDK5R1 Antikörper
Human, Maus, Ratte
Wirt
Alle Wirte für CDK5R1 Antikörper
Kaninchen
Klonalität
Alle Klonalitäten für CDK5R1 Antikörper
Polyklonal
Konjugat
Alle Konjugate für CDK5R1 Antikörper
Dieser CDK5R1 Antikörper ist unkonjugiert
Applikation
Alle Applikationen für CDK5R1 Antikörper
Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Spezifität
This antibody detects endogenous levels of p35 protein. (region surrounding Gln31)
Kreuzreaktivität (Details)
Species reactivity (expected):Mouse and Rat. Species reactivity (tested):Human.
Aufreinigung
Affinity Chromatography using epitope-specific immunogen.
Top Product
Discover our top product CDK5R1 Primärantikörper
Alternativen
(anzeigen)
Anwendungsinformationen
(ausblenden)
Applikationshinweise
ELISA: 1: 20000approx. 1: 40000. WB: 1: 500approx. 1: 1000. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
(ausblenden)
Konzentration
1.0 mg/mL
Buffer
Phosphate buffered saline (PBS), pH ~7.2, 0.05 % Sodium Azide
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung
Avoid repeated freezing and thawing.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Details zu CDK5R1
(ausblenden)
Target
CDK5R1
(Cyclin-Dependent Kinase 5, Regulatory Subunit 1 (p35) (CDK5R1))
Andere Bezeichnung
CDK5R1 (CDK5R1 Produkte )
Synonyme
CDK5P35 antikoerper, CDK5R antikoerper, NCK5A antikoerper, p23 antikoerper, p25 antikoerper, p35 antikoerper, p35nck5a antikoerper, cdk5r1 antikoerper, zgc:92814 antikoerper, CDK5R1 antikoerper, Cdk5r antikoerper, P25/P35 antikoerper, D11Bwg0379e antikoerper, Xp35.1 antikoerper, cyclin dependent kinase 5 regulatory subunit 1 antikoerper, cyclin-dependent kinase 5, regulatory subunit 1b (p35) antikoerper, cyclin-dependent kinase 5 regulatory subunit 1 antikoerper, S100 calcium binding protein A9 antikoerper, cyclin-dependent kinase 5, regulatory subunit 1 (p35) antikoerper, cyclin-dependent kinase 5, regulatory subunit 1 (p35) L homeolog antikoerper, CDK5R1 antikoerper, cdk5r1b antikoerper, Cdk5r1 antikoerper, S100A9 antikoerper, cdk5r1.L antikoerper
Substanzklasse
Viral Protein
Hintergrund
Cyclin dependent kinase-5 (Cdk5), a key regulator of cell cycle progression, was originally isolated on the basis of its structural homology to Cdc2, a wellcharacterized regulator of cell cycle progression. Although Cdk5 is expressed at the highest level in the brain of adult mice, intermediate levels in testis and low or undetectable levels in all other tissues, brain is the only tissue from which Cdk5 can be isolated as an active kinase. These findings may be explained by the cloning and characterization of a Cdk5 regulatory subunit, designated p35. p35 displays a neuronal cell-specific pattern of expression, physically associates with Cdk5 and activates Cdk5 enzymatic activity. p35 is also expressed in many tissues in a truncated form, designated p25.
Molekulargewicht
approx. 38 kDa
Gen-ID
8851
NCBI Accession
NP_003876
UniProt
Q15078
Pathways
Stem Cell Maintenance , Regulation of Cell Size , Positive Regulation of Endopeptidase Activity
Zuletzt angesehen
(ausblenden)