HOXB9 Antikörper

Produktnummer ABIN272173

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch HOXB9 in WB und IHC (p). Es zeigt Reaktivität gegenüber Proben von Human und Maus.

Kurzübersicht für HOXB9 Antikörper (ABIN272173)

Target: HOXB9 (Homeobox B9 (HOXB9))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HOXB9 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-HOXB9 Antikörper

Spezifität: This antibody detects endogenous levels of Hox-B9 protein. (region surrounding Arg237)

Kreuzreaktivität (Details): Species reactivity (tested):Human, Mouse.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Reinheit: > 95 % pure by SDS-PAGE

Anwendungsinformationen

Applikationshinweise: ELISA: 1: 10000approx. 1: 20000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1,0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: DO NOT FREEZE!

Lagerung: 4 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C.

Details zu HOXB9

Target: HOXB9 (Homeobox B9 (HOXB9))

Andere Bezeichnung: HOXB9 / HOX2E

Hintergrund: The Hox proteins play a role in development and cellular differentiation by regulating downstream target genes. Specifically, the Hox proteins direct DNA-protein and protein-protein interactions that assist in determining the morphologic features associated with the anterior-posterior body axis. Themammalian Hox gene complex consists of 39 genes that are located on four linkage groups, which are dispersed over four chromosomes. Hox genes that occupy the same relative position along the 5' to 3' coordinate (trans-paralogous genes) are more similar in sequence and expression pattern than adjacent Hox genes on the same chromosome. In mice, the HoxB cluster contains HoxB1 to HoxB9 and HoxB13, which are transcribed in the same direction. HoxB9 associates with the transcriptional cofactors BTG1 and BTG2, which enhance HoxB9 ranscription. Alterations in HoxB9 expression, as with other Hox family member, has been implicated in leukemia.Synonyms: Homeobox protein Hox-B9, Hox-2.5, Hox-2E

Molekulargewicht: approx. 28 kDa

Gen-ID: 3219

NCBI Accession: NP_076922

UniProt: P17482