HNRNPL Antikörper
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- Target Alle HNRNPL Antikörper anzeigen
- HNRNPL (Heterogeneous Nuclear Ribonucleoprotein L (HNRNPL))
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Reaktivität
- Human, Maus
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser HNRNPL Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Spezifität
- This antibody detects endogenous levels of hnRNP L protein. (region surrounding Gly58)
- Kreuzreaktivität (Details)
- Species reactivity (tested):Human, Mouse.
- Aufreinigung
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
- Reinheit
- > 95 % pure by SDS-PAGE
- Top Product
- Discover our top product HNRNPL Primärantikörper
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- Applikationshinweise
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ELISA: 1: 20000approx. 1: 40000. WB: 1: 500approx. 1: 1000. IHC: 1: 50approx. 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 1,0 mg/mL
- Buffer
- Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- DO NOT FREEZE!
- Lagerung
- 4 °C
- Informationen zur Lagerung
- Store the antibody undiluted at 2-8 °C.
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- Target
- HNRNPL (Heterogeneous Nuclear Ribonucleoprotein L (HNRNPL))
- Andere Bezeichnung
- HnRNP-L / HNRNPL (HNRNPL Produkte)
- Synonyme
- HNRPL antikoerper, hnRNP-L antikoerper, zgc:55429 antikoerper, HNRNPL antikoerper, hnrpl antikoerper, C79783 antikoerper, D830027H13Rik antikoerper, Hnrpl antikoerper, hnrnp-L antikoerper, heterogeneous nuclear ribonucleoprotein L antikoerper, HNRNPL antikoerper, hnrpl antikoerper, hnrnpl antikoerper, Hnrnpl antikoerper
- Hintergrund
- Heterogeneous nuclear ribonucleoproteins (hnRNPs) constitute a set of polypeptides that contribute to mRNA transcription, pre-mRNA processing and mature mRNA transport to the cytoplasm and translation. They also bind heterogeneous nuclear RNA (hnRNA), which are the transcripts produced by RNA polymerase II). There are approximately 20 known hnRNP proteins, which range in size from 34 kDa to 120 kDa, and their complexes are the majorconstituents of the spliceosome. The majority of hnRNP proteins components are localized to the nucleus, however some shuttle between the nucleus and the cytoplasm. hnRNP I, also designated polypyrimidine tract-binding protein (PTB) and its homolog hnRNP L bind to the 3' end of introns to modulate alternative splicing mechanisms of pre-mRNAs in normal cells and the translation of several viruses, including hepatitis C virus (HCV). The human hnRNP I gene maps to chromosome 19p13.3 and encodes a 57 kDa protein that is localized in the nucleoplasm. hnRNP L has a molecular mass of 68 kDa and like hnRNP I, is also localized in the nucleoplasm.Synonyms: HNRPL, Heterogeneous nuclear ribonucleoprotein L, P/OKcl.14
- Molekulargewicht
- approx. 60 kDa
- Gen-ID
- 3191
- NCBI Accession
- NP_001005335
- UniProt
- P14866
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