Tyrosine Hydroxylase Antikörper
Kurzübersicht für Tyrosine Hydroxylase Antikörper (ABIN272085)
Target
Alle Tyrosine Hydroxylase (TH) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Spezifität
- This antibody detects endogenous levels of TH protein. (region surrounding Pro2)
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Kreuzreaktivität (Details)
- Species reactivity (tested):Mouse and Rat.
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Aufreinigung
- Affinity Chromatography using epitope-specific immunogen.
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anti-Tyrosine Hydroxylase (TH) antibody
TH Reaktivität: Human, Ratte, Maus, Hund, Kaninchen, Huhn, Drosophila melanogaster, Schwein, Zebrafisch (Danio rerio), Xenopus laevis, Meerschweinchen, Cat, Frettchen, Salmon, Salamander, Saccharomyces cerevisiae, Nagetiere, Wachtel, Polypterus senegalus, Taube, Phoronida, Parrot (Melopsittacus), Parrot, Opossum, Onchocerca, Molch, Zebra Finch, Mollusca, Sea Pansy, Sea Slug, Serinus canaria, Hai, Schaf, Spitzmaus, Snail, Schlange, Spatz, Squirrel Monkey, Starling, Forelle, Pute, Schildkröte, Water Buffalo, Emu, Alpaca, Amphibien, Aplysia californica, Avian, Bee, Blow Fly, Clams (Mytilus), Cockroach, Kabeljau, Koralle, Crab, Crayfish, Cynomolgus, Echidna, Macrobrachium rosenbergii (Giant fresh water prawn), Fisch, Fuchs, Frosch, Gecko, Wüstenrennmaus, Goldfisch, Guppy, Hamster, Iguana iguana, Lamprey, Blutegel, Eidechse, Hummer, Locust (Schistocerca) WB, IHC, IF, ICC, IEM Wirt: Maus Monoclonal LNC1 unconjugated
anti-Tyrosine Hydroxylase (TH) (AA 82-310) antibodyTH Reaktivität: Human WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Tyrosine Hydroxylase (TH) (AA 101-165) antibodyTH Reaktivität: Human, Ratte, Maus WB, ELISA, IHC (p), IHC (fro), IF (cc), IF (p) Wirt: Kaninchen Polyclonal unconjugated
anti-Tyrosine Hydroxylase (TH) antibodyTH Reaktivität: Human WB, IF, ICC, IHC (p), IHC (fro), IHC (wm) Wirt: Kaninchen Polyclonal unconjugated
anti-Tyrosine Hydroxylase (TH) (pSer40) antibodyTH Reaktivität: Human, Ratte, Maus WB, IHC, IF, ELISA, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Tyrosine Hydroxylase (TH) (pSer31) antibodyTH Reaktivität: Human, Ratte, Maus WB, IHC, IF, ELISA, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Tyrosine Hydroxylase (TH) (AA 486-514) antibodyTH Reaktivität: Human WB, IHC, ELISA, FACS Wirt: Kaninchen Polyclonal unconjugated
anti-Tyrosine Hydroxylase (TH) (AA 34-301) antibodyTH Reaktivität: Ratte WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Tyrosine Hydroxylase (TH) (pSer19) antibodyTH Reaktivität: Human, Ratte, Maus WB, IHC, IF, ELISA, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Tyrosine Hydroxylase (TH) (AA 193-222), (Middle Region) antibodyTH Reaktivität: Ratte, Maus WB, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
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Applikationshinweise
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ELISA: 1/20000approx. 1/40000. Western Blot: 1/500approx. 1/1000. Immunohistochemistry: 1/50approx. 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1,0 mg/mL
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Buffer
- Phosphate buffered saline (PBS), pH ~7.2, 0.05 % Sodium Azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freezing and thawing.
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Lagerung
- 4 °C/-20 °C
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Informationen zur Lagerung
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Tyrosine Hydroxylase (TH)
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Andere Bezeichnung
- Tyrosine 3-Monooxygenase (TH)
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Hintergrund
- The enzyme tyrosine hydroxylase (TH), also designated tyrosine 3-monooxygenase (TY3H), catalyzes the conversion of tyrosine to L-dopa, which is the rate limiting step in the biosynthesis of catecholamines such as dopamine, adrenalin and noradrenalin. TH is thought to play a role in the pathogenesis of Parkinson's disease, which is associated with reduced dopamine levels. Two transcription factor binding sites in the proximal region of the TH gene, the TPA-responsive element (TRE) and the c-AMP responsive element (CRE), have been implicated in the complex regulation of the TH gene. TH is also known to be upregulated by the glia maturation factor (GMF), a Cdc 10/SWI6 motif-containing protein called V-1, and a variety of additional compounds.Synonyms: TYH, Tyrosine 3-hydroxylase
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Molekulargewicht
- approx. 58 kDa
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Gen-ID
- 25085
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NCBI Accession
- NP_036872
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UniProt
- P04177
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Pathways
- Dopaminergic Neurogenesis, Response to Water Deprivation, Sensory Perception of Sound, Carbohydrate Homeostasis, Feeding Behaviour
Target
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