SOX9 Antikörper

Produktnummer ABIN272082

Zitiert in 3+ Publikationen. Der Kaninchen Polyklonal anti-SOX9 Antikörper (ABIN272082) detektiert spezifisch SOX9 in WB, IF und IHC (p). Dieser Antikörper reagiert spezifisch mit Proben aus Human und Maus.

Kurzübersicht für SOX9 Antikörper (ABIN272082)

Target: SOX9 (SRY (Sex Determining Region Y)-Box 9 (SOX9))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SOX9 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-SOX9 Antikörper

Spezifität: This antibody detects endogenous levels of SOX-9 protein. (region surrounding Gln175).

Kreuzreaktivität (Details): Species reactivity (tested):Human and Mouse.

Aufreinigung: Affinity Chromatography using epitope-specific immunogen

Anwendungsinformationen

Applikationshinweise: ELISA: 1/5000approx. 1/10000Western Blot: 1/500approx. 1/1000Immunohistochemistry (Paraffin): 1/50approx. 1/200Immunofluorescence: 1/50approx. 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH ~7.2, 0.05 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Referenzen für anti-SOX9 Antikörper (ABIN272082)

Ichikawa, Watahiki, Nampo, Nose, Yamamoto, Irie, Mishima, Maki: "Differences in the developmental origins of the periosteum may influence bone healing." in: Journal of periodontal research, Vol. 50, Issue 4, pp. 468-78, (2016) (PubMed).

Zhang, Ding, Nie, Li-Ling, Zhang, Zhang, Chen, Li, Ding: "Association of hsa-miR‑145 overexpression in human testicular cells with male infertility." in: Molecular medicine reports, Vol. 11, Issue 6, pp. 4365-72, (2015) (PubMed).

Nagappan, Park, Park, Kim, Hong, Kang, Zhang, Kim, Lee, Won, Kim: "Proteomic analysis of differentially expressed proteins in vitamin C-treated AGS cells." in: BMC biochemistry, Vol. 14, pp. 24, (2014) (PubMed).

Details zu SOX9

Target: SOX9 (SRY (Sex Determining Region Y)-Box 9 (SOX9))

Andere Bezeichnung: SOX9

Hintergrund: Sox genes comprise a family of genes that are related to the mammalian sex determining gene SRY. These genes similarly contain sequences that encode for the HMG-box domain, which is responsible for the sequence-specific DNA-binding activity. Sox genes encode putative transcriptional regulators implicated in the decision of cell fates during development and the control of diverse developmental processes. The highly complex group of Sox genes cluster at least 40 different loci that rapidly diverged in various animal lineages. At present, 30 Sox genes have been identified. Members of this family have been shown to be conserved during evolution and to play key roles during animal development. Some are involved in human diseases, including sex reversal.Synonyms: CMD1, CMPD1, SRA1, SRY (sex determining region Y)-box 9, SRY-box 9, Transcription factor SOX-9

Molekulargewicht: approx. 56 kDa

Gen-ID: 6662

NCBI Accession: NP_000337

UniProt: P48436

Pathways: EGFR Signaling Pathway, Stem Cell Maintenance, Regulation of Muscle Cell Differentiation, Tube Formation, Skeletal Muscle Fiber Development