DOK7 Antikörper

Produktnummer ABIN2719662

Produktdetails anti-DOK7 Antikörper

Target: DOK7 (Docking Protein 7 (DOK7))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser DOK7 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)

Produktmerkmale: Homo sapiens docking protein 7 (DOK7), transcript variant 1

Aufreinigung: Purified from mouse ascites fluids by affinity chromatography

Immunogen: Full length human recombinant protein of human DOK7(NP_775931) produced in HEK293T cell.

Klon: 7E2

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: WB 1:2000, IHC 1:150, FLOW 1:100,

Kommentare:

The concentration of the product may vary between diferrent lots.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5-1.0 mg/mL

Buffer: PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Details zu DOK7

Target: DOK7 (Docking Protein 7 (DOK7))

Andere Bezeichnung: DOK7 (DOK7 Produkte)

Hintergrund: The protein encoded by this gene is essential for neuromuscular synaptogenesis. The protein functions in aneural activation of muscle-specific receptor kinase, which is required for postsynaptic differentiation, and in the subsequent clustering of the acetylcholine receptor in myotubes. This protein can also induce autophosphorylation of muscle-specific receptor kinase. Mutations in this gene are a cause of familial limb-girdle myasthenia autosomal recessive, which is also known as congenital myasthenic syndrome type 1B. Alternative splicing results in multiple transcript variants.

Molekulargewicht: 52.9 kDa

Gen-ID: 285489

NCBI Accession: NM_173660

HGNC: 285489

Pathways: Skeletal Muscle Fiber Development