DAND5 Antikörper (AA 23-189)

Produktnummer ABIN2719202

Produktdetails anti-DAND5 Antikörper

Target: DAND5 (DAN Domain Family, Member 5 (DAND5))

Bindungsspezifität: AA 23-189

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser DAND5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)

Produktmerkmale: Homo sapiens DAN domain family, member 5 (DAND5)

Aufreinigung: Purified from mouse ascites fluids by affinity chromatography

Immunogen: Human recombinant protein fragment corresponding to amino acids 23-189 of human DAND5(NP_689867) produced in E.coli.

Klon: 2H3

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: WB 1:500~2000, IHC 1:150, FLOW 1:100,

Kommentare:

The concentration of the product may vary between diferrent lots.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5-1.0 mg/mL

Buffer: PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Details zu DAND5

Target: DAND5 (DAN Domain Family, Member 5 (DAND5))

Andere Bezeichnung: DAND5 (DAND5 Produkte)

Hintergrund: This gene encodes a member of the BMP (bone morphogenic protein) antagonist family. Like BMPs, BMP antagonists contain cystine knots and typically form homo- and heterodimers. The CAN (cerberus and dan) subfamily of BMP antagonists, to which this gene belongs, is characterized by a C-terminal cystine knot with an eight-membered ring. The antagonistic effect of the secreted protein encoded by this gene is likely due to its direct binding to BMP proteins. As an antagonist of BMP, this gene may play a role in regulating organogenesis, body patterning, and tissue differentiation. In mouse, this protein has been shown to bind Nodal and to inhibit the Nodal signaling pathway which patterns left/right body asymmetry.

Molekulargewicht: 18 kDa

Gen-ID: 199699

NCBI Accession: NM_152654

HGNC: 199699