SNAP25 Antikörper

Produktnummer ABIN271818

Produktdetails anti-SNAP25 Antikörper

Target: SNAP25 (Synaptosomal-Associated Protein, 25kDa (SNAP25))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SNAP25 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Spezifität: This antibody detects endogenous levels of SNAP25 protein. (region surrounding Glu183)

Kreuzreaktivität (Details): Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.

Aufreinigung: Affinity Chromatography using epitope-specific immunogen

Anwendungsinformationen

Applikationshinweise: ELISA: 1/20000-1/40000. Western Blot: 1/500-1/1000. Immunohistochemistry: 1/50-1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH ~7.2, 0.05 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu SNAP25

Target: SNAP25 (Synaptosomal-Associated Protein, 25kDa (SNAP25))

Andere Bezeichnung: SNAP25 (SNAP25 Produkte)

Synonyme: RIC-4 antikoerper, RIC4 antikoerper, SEC9 antikoerper, SNAP antikoerper, SNAP-25 antikoerper, bA416N4.2 antikoerper, dJ1068F16.2 antikoerper, SNAP-25B antikoerper, SNAP-25a antikoerper, ric-4 antikoerper, ric4 antikoerper, sec9 antikoerper, snap-25 antikoerper, Bdr antikoerper, sp antikoerper, fj55h11 antikoerper, snap25 antikoerper, wu:fj55h11 antikoerper, Snap antikoerper, snap25.2 antikoerper, wu:fj33h05 antikoerper, synaptosome associated protein 25 antikoerper, synaptosome associated protein 25kDa S homeolog antikoerper, synaptosomal-associated protein, 25kDa antikoerper, synaptosomal-associated protein 25 antikoerper, synaptosome associated protein 25kDa antikoerper, synaptosome associated protein 25kDa L homeolog antikoerper, zgc:101731 antikoerper, synaptosomal-associated protein, 25b antikoerper, SNAP25 antikoerper, Snap25 antikoerper, snap25.S antikoerper, snap25 antikoerper, BACOIKO003_07 antikoerper, Tsp_10811 antikoerper, snap25.L antikoerper, zgc:101731 antikoerper, snap25b antikoerper

Hintergrund: Syntaxins, six of which have been identified, were originally thought to be docking proteins, but have more recently been categorized as anchoring proteins that anchor themselves to the cytoplasmic surfaces of cellular membranes. Syntaxins have been shown to bind to various proteins involved in exocytosis, including VAMPs (vesicle-associated membrane proteins), NSF(N-ethylmaleimide-sensitive factor), SNAP 25, SNAPs (soluble NSF attachment proteins) and synap-totagmin. VAMPs (also designated synaptobrevins), including VAMP-1 and VAMP-2, and Synaptotagmin, a protein that may function as an inhibitor of exocytosis, are vesicular proteins. SNAPs, including alpha- and gamma-SNAP, are cytoplasmic proteins that bind to a membrane receptor complex composed of VAMP, SNAP 25 and syntaxin. SNAPs mediate the membrane binding of NSF, which is essential for membrane fusion reactions. An additional protein designated synaptophysin may regulate exocytosis bycompeting with SNAP 25 and syntaxins for VAMP binding.Synonyms: RIC4, SNAP, SNAP-25, SUP, Super Protein, Synaptosomal-associated 25 kDa protein, Synaptosomal-associated protein 25, ric-4

Molekulargewicht: approx. 23 kDa

Gen-ID: 6616

NCBI Accession: NP_003072

UniProt: P60880

Pathways: Positive Regulation of Peptide Hormone Secretion, Hormone Transport, Synaptic Vesicle Exocytosis, Dicarboxylic Acid Transport