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SNAP25 Antikörper

SNAP25 Reaktivität: Human, Maus, Ratte EIA, IHC (p), WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN271818
$603.60
Zzgl. Versandkosten $45.00
0.1 mg
Available
  • Target Alle SNAP25 Antikörper anzeigen
    SNAP25 (Synaptosomal-Associated Protein, 25kDa (SNAP25))
    Reaktivität
    • 112
    • 72
    • 69
    • 11
    • 11
    • 10
    • 10
    • 10
    • 8
    • 7
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 103
    • 33
    • 9
    • 4
    • 1
    Kaninchen
    Klonalität
    • 109
    • 38
    • 1
    Polyklonal
    Konjugat
    • 85
    • 10
    • 7
    • 5
    • 5
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser SNAP25 Antikörper ist unkonjugiert
    Applikation
    • 92
    • 62
    • 34
    • 16
    • 13
    • 13
    • 13
    • 12
    • 12
    • 10
    • 9
    • 8
    • 7
    • 2
    • 2
    • 1
    • 1
    • 1
    Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
    Spezifität
    This antibody detects endogenous levels of SNAP25 protein. (region surrounding Glu183)
    Kreuzreaktivität (Details)
    Species reactivity (expected):Mouse and Rat.
    Species reactivity (tested):Human.
    Aufreinigung
    Affinity Chromatography using epitope-specific immunogen
  • Applikationshinweise
    ELISA: 1/20000-1/40000. Western Blot: 1/500-1/1000. Immunohistochemistry: 1/50-1/200.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    1.0 mg/mL
    Buffer
    Phosphate buffered saline (PBS), pH ~7.2, 0.05 % Sodium Azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target
    SNAP25 (Synaptosomal-Associated Protein, 25kDa (SNAP25))
    Andere Bezeichnung
    SNAP25 (SNAP25 Produkte)
    Synonyme
    ric-4, ric4, sec9, snap-25, SNAP-25B, SNAP-25a, Bdr, SNAP-25, sp, RIC-4, RIC4, SEC9, SNAP, bA416N4.2, dJ1068F16.2, fj55h11, snap25, wu:fj55h11, synaptosome associated protein 25kDa S homeolog, synaptosome associated protein 25kDa, synaptosomal-associated protein 25, synaptosome associated protein 25kDa L homeolog, synaptosome associated protein 25, synaptosomal-associated protein, 25kDa, zgc:101731, snap25.S, snap25, BACOIKO003_07, Tsp_10811, snap25.L, Snap25, SNAP25, zgc:101731
    Hintergrund
    Syntaxins, six of which have been identified, were originally thought to be docking proteins, but have more recently been categorized as anchoring proteins that anchor themselves to the cytoplasmic surfaces of cellular membranes. Syntaxins have been shown to bind to various proteins involved in exocytosis, including VAMPs (vesicle-associated membrane proteins), NSF(N-ethylmaleimide-sensitive factor), SNAP 25, SNAPs (soluble NSF attachment proteins) and synap-totagmin. VAMPs (also designated synaptobrevins), including VAMP-1 and VAMP-2, and Synaptotagmin, a protein that may function as an inhibitor of exocytosis, are vesicular proteins. SNAPs, including alpha- and gamma-SNAP, are cytoplasmic proteins that bind to a membrane receptor complex composed of VAMP, SNAP 25 and syntaxin. SNAPs mediate the membrane binding of NSF, which is essential for membrane fusion reactions. An additional protein designated synaptophysin may regulate exocytosis bycompeting with SNAP 25 and syntaxins for VAMP binding.Synonyms: RIC4, SNAP, SNAP-25, SUP, Super Protein, Synaptosomal-associated 25 kDa protein, Synaptosomal-associated protein 25, ric-4
    Molekulargewicht
    approx. 23 kDa
    Gen-ID
    6616
    NCBI Accession
    NP_003072
    UniProt
    P60880
    Pathways
    Positive Regulation of Peptide Hormone Secretion, Hormone Transport, Synaptic Vesicle Exocytosis, Dicarboxylic Acid Transport
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