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SNAP25 Antikörper

Dieses Anti-SNAP25-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von SNAP25 in WB, IHC (p) und EIA. Geeignet für Human, Ratte und Maus.
Produktnummer ABIN271818

Kurzübersicht für SNAP25 Antikörper (ABIN271818)

Target

Alle SNAP25 Antikörper anzeigen
SNAP25 (Synaptosomal-Associated Protein, 25kDa (SNAP25))

Reaktivität

  • 103
  • 76
  • 70
  • 10
  • 10
  • 9
  • 8
  • 8
  • 7
  • 6
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Human, Ratte, Maus

Wirt

  • 104
  • 24
  • 4
  • 3
  • 1
Kaninchen

Klonalität

  • 100
  • 33
  • 1
Polyklonal

Konjugat

  • 80
  • 8
  • 5
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser SNAP25 Antikörper ist unkonjugiert

Applikation

  • 97
  • 48
  • 35
  • 23
  • 20
  • 18
  • 13
  • 13
  • 13
  • 12
  • 8
  • 4
  • 4
  • 2
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
  • Spezifität

    This antibody detects endogenous levels of SNAP25 protein. (region surrounding Glu183)

    Kreuzreaktivität (Details)

    Species reactivity (expected):Mouse and Rat.
    Species reactivity (tested):Human.

    Aufreinigung

    Affinity Chromatography using epitope-specific immunogen
  • Applikationshinweise

    ELISA: 1/20000-1/40000. Western Blot: 1/500-1/1000. Immunohistochemistry: 1/50-1/200.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Konzentration

    1.0 mg/mL

    Buffer

    Phosphate buffered saline (PBS), pH ~7.2, 0.05 % Sodium Azide

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handhabung

    Avoid repeated freezing and thawing.

    Lagerung

    4 °C/-20 °C

    Informationen zur Lagerung

    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target

    SNAP25 (Synaptosomal-Associated Protein, 25kDa (SNAP25))

    Andere Bezeichnung

    SNAP25

    Hintergrund

    Syntaxins, six of which have been identified, were originally thought to be docking proteins, but have more recently been categorized as anchoring proteins that anchor themselves to the cytoplasmic surfaces of cellular membranes. Syntaxins have been shown to bind to various proteins involved in exocytosis, including VAMPs (vesicle-associated membrane proteins), NSF(N-ethylmaleimide-sensitive factor), SNAP 25, SNAPs (soluble NSF attachment proteins) and synap-totagmin. VAMPs (also designated synaptobrevins), including VAMP-1 and VAMP-2, and Synaptotagmin, a protein that may function as an inhibitor of exocytosis, are vesicular proteins. SNAPs, including alpha- and gamma-SNAP, are cytoplasmic proteins that bind to a membrane receptor complex composed of VAMP, SNAP 25 and syntaxin. SNAPs mediate the membrane binding of NSF, which is essential for membrane fusion reactions. An additional protein designated synaptophysin may regulate exocytosis bycompeting with SNAP 25 and syntaxins for VAMP binding.Synonyms: RIC4, SNAP, SNAP-25, SUP, Super Protein, Synaptosomal-associated 25 kDa protein, Synaptosomal-associated protein 25, ric-4

    Molekulargewicht

    approx. 23 kDa

    Gen-ID

    6616

    NCBI Accession

    NP_003072

    UniProt

    P60880

    Pathways

    Positive Regulation of Peptide Hormone Secretion, Hormone Transport, Synaptic Vesicle Exocytosis, Dicarboxylic Acid Transport
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