RIT1 Antikörper
Kurzübersicht für RIT1 Antikörper (ABIN271808)
Target
Alle RIT1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Spezifität
- This antibody detects endogenous levels of ROC1 protein. (region surrounding Trp204)
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Kreuzreaktivität (Details)
- Species reactivity (tested):Human and Mouse.
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Aufreinigung
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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Reinheit
- > 95 % pure by SDS-PAGE
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Applikationshinweise
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ELISA: 1: 10000approx. 1: 20000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1,0 mg/mL
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Buffer
- Phosphate buffered saline (PBS), pH 7.2., 15 mM sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- DO NOT FREEZE!
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Lagerung
- 4 °C
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Informationen zur Lagerung
- Store the antibody undiluted at 2-8 °C.
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- RIT1 (Ras-Like Without CAAX 1 (RIT1))
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Andere Bezeichnung
- RIT1
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Hintergrund
- ROC 1 and ROC 2 are the two highly conserved RING finger proteins that are homologous to APC 11, a subunit of the anaphase promoting complex(APC). ROC 1 and ROC 2 commonly interact with all cullins while APC 11 specifically interacts with APC 2, a cullin related APC subunit. ROC 1 and APC 11 immunocomplexes can catalyze isopeptide ligations to form polyubiquitin chains in an E1 and E2 dependent manner. ROC 1 is thought to play a unique role in the ubiquitination reaction by heterodimerizing with cullin 1 to catalyze ubiquitin polymerization.Synonyms: RIBB, RIT, ROC1, Ras-like protein expressed in many tissues, Ras-like without CAAX protein 1
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Molekulargewicht
- approx. 25 kDa
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Gen-ID
- 6016
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NCBI Accession
- NP_008843
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UniProt
- Q92963
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Pathways
- Neurotrophin Signalübertragung
Target
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