Peripherin Antikörper

Produktnummer ABIN271783

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch Peripherin in WB und IHC (p). Es zeigt Reaktivität gegenüber Proben von Human und Ratte.

Kurzübersicht für Peripherin Antikörper (ABIN271783)

Target: Peripherin (PRPH)

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Peripherin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-Peripherin Antikörper

Spezifität: This antibody detects endogenous levels of Peripherin protein. (region surrounding Ser454)

Kreuzreaktivität (Details): Species reactivity (tested):Human, Rat.

Aufreinigung: Affinity Chromatography using epitope-specific immunogen.

Anwendungsinformationen

Applikationshinweise: ELISA: 1: 5000approx. 1: 20000. WB: 1: 500approx. 1: 1000. IHC: 1: 50approx. 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.2., 0.05 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu Peripherin

Target: Peripherin (PRPH)

Andere Bezeichnung: Peripherin

Hintergrund: Peripherin is a type III intermediate filament protein that is expressed in peripheral and some central nervous system (CNS) neurons. Peripherin activation is known to be induced by leukemia inhibitory factor (LIF). LIF activates Peripherin by inducing members of STAT transcription factor family to bind to a specific promoter element in the Peripherin gene. IL-6 is also known to induce Peripherin expression. Although it is not essential for neurite formation, peripherin is necessary for cellular intermediate filament network formation. Peripherin, unlike most intermediate filament proteins, has been reported to be modified by tyrosine phosphorylation.Synonyms: NEF4, PRPH, PRPH1

Molekulargewicht: approx. 55 kDa

Gen-ID: 5630

NCBI Accession: NP_006253

UniProt: P41219