Catalase Antikörper

Produktnummer ABIN2717106

Der Maus Monoklonal Anti-Catalase-Antikörper wurde für WB, IHC und IF validiert. Er ist geeignet, Catalase in Proben von Human, Ratte, Hund und Affe zu detektieren. Es ist 1 Publikation verfügbar.

Kurzübersicht für Catalase Antikörper (ABIN2717106)

Target: Catalase (CAT)

Reaktivität: Human, Ratte, Hund, Affe

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Catalase Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Klon: 1B6

Produktdetails anti-Catalase Antikörper

Produktmerkmale: Homo sapiens catalase (CAT)

Aufreinigung: Purified from mouse ascites fluids by affinity chromatography

Immunogen: Full length human recombinant protein of human CAT (NP_111743) produced in HEK293T cell.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: WB 1:200~500, IHC 1:150, IF 1:100,

Kommentare:

The concentration of the product may vary between diferrent lots.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5-1.0 mg/mL

Buffer: PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Referenzen für anti-Catalase Antikörper (ABIN2717106)

Benlloch, Obrador, Valles, Rodriguez, Sirerol, Alcácer, Pellicer, Salvador, Cerdá, Sáez, Estrela: "Pterostilbene Decreases the Antioxidant Defenses of Aggressive Cancer Cells In Vivo: A Physiological Glucocorticoids- and Nrf2-Dependent Mechanism." in: Antioxidants & redox signaling, Vol. 24, Issue 17, pp. 974-90, (2016) (PubMed).

Details zu Catalase

Target: Catalase (CAT)

Andere Bezeichnung: CAT

Hintergrund: This gene encodes catalase, a key antioxidant enzyme in the bodies defense against oxidative stress. Catalase is a heme enzyme that is present in the peroxisome of nearly all aerobic cells. Catalase converts the reactive oxygen species hydrogen peroxide to water and oxygen and thereby mitigates the toxic effects of hydrogen peroxide. Oxidative stress is hypothesized to play a role in the development of many chronic or late-onset diseases such as diabetes, asthma, Alzheimer's disease, systemic lupus erythematosus, rheumatoid arthritis, and cancers. Polymorphisms in this gene have been associated with decreases in catalase activity but, to date, acatalasemia is the only disease known to be caused by this gene.

Molekulargewicht: 59.6 kDa

Gen-ID: 847

NCBI Accession: NM_001752

HGNC: 847

Pathways: Cellular Glucan Metabolic Process, Cell RedoxHomeostasis, Photoperiodism