Bestrophin 3 Antikörper
Kurzübersicht für Bestrophin 3 Antikörper (ABIN2716602)
Target
Alle Bestrophin 3 (BEST3) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Produktmerkmale
- Homo sapiens bestrophin 3 (BEST3), transcript variant 2
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Aufreinigung
- Purified from mouse ascites fluids by affinity chromatography
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Immunogen
- Full length human recombinant protein of human BEST3 (NP_689652) produced in HEK293T cell.
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Isotyp
- IgG2a
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Applikationshinweise
- WB 1:2000, IF 1:100, FLOW 1:100
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Kommentare
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The concentration of the product may vary between diferrent lots.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 0.5-1.0 mg/mL
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Buffer
- PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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- Bestrophin 3 (BEST3)
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Andere Bezeichnung
- BEST3
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Hintergrund
- BEST3 belongs to the bestrophin family of anion channels, which includes BEST1 (MIM 607854), the gene mutant in vitelliform macular dystrophy (VMD, MIM 153700), and 2 other BEST1-like genes, BEST2 (MIM 607335) and BEST4 (MIM 607336). Bestrophins are transmembrane (TM) proteins that share a homology region containing a high content of aromatic residues, including an invariant arg-phe-pro (RFP) motif. The bestrophin genes share a conserved gene structure, with almost identical sizes of the 8 RFP-TM domain-encoding exons and highly conserved exon-intron boundaries. Each of the 4 bestrophin genes has a unique 3-prime end of variable length (Stohr et al., 2002 [PubMed 12032738], Tsunenari et al., 2003 [PubMed 12907679]).
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Molekulargewicht
- 50.8 kDa
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Gen-ID
- 144453
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NCBI Accession
- NM_152439
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HGNC
- 144453
Target
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