ZFYVE9 Antikörper (AA 71-170) (Cy5)
Kurzübersicht für ZFYVE9 Antikörper (AA 71-170) (Cy5) (ABIN2690277)
Target
Alle ZFYVE9 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 71-170
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Kreuzreaktivität
- Human
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Aufreinigung
- Purified by Protein A.
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Immunogen
- KLH conjugated synthetic peptide derived from human SARA
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Isotyp
- IgG
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Applikationshinweise
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 μg/μL
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Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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Haltbarkeit
- 12 months
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- ZFYVE9 (Zinc Finger, FYVE Domain Containing 9 (ZFYVE9))
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Andere Bezeichnung
- SARA
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Hintergrund
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Synonyms: NSP, SARA, MADHIP, SMADIP, PPP1R173, Zinc finger FYVE domain-containing protein 9, Mothers against decapentaplegic homolog-interacting protein, Madh-interacting protein, Novel serine protease, Receptor activation anchor, hSARA, Smad anchor for receptor activation, ZFYVE9
Background: Early endosomal protein that functions to recruit SMAD2/SMAD3 to intracellular membranes and to the TGF-beta receptor. Plays a significant role in TGF-mediated signaling by regulating the subcellular location of SMAD2 and SMAD3 and modulating the transcriptional activity of the SMAD3/SMAD4 complex. Possibly associated with TGF-beta receptor internalization.
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Gen-ID
- 9372
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UniProt
- O95405
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Pathways
- Protein targeting to Nucleus
Target
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