OPRD1 Antikörper (AA 81-180)

Produktnummer ABIN2690091

Dieser Anti-OPRD1 Antikörper ist ein Kaninchen Polyklonal Antikörper zur Detektion von OPRD1 in WB, ELISA, IF (cc), IF (p) und ICC. Geeignet für Human, Maus und Ratte. Dieses Primary Antibody wurde in 1 Publikation zitiert.

Kurzübersicht für OPRD1 Antikörper (AA 81-180) (ABIN2690091)

Target: OPRD1 (Opioid Receptor, delta 1 (OPRD1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser OPRD1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunocytochemistry (ICC)

Produktdetails anti-OPRD1 Antikörper

Bindungsspezifität: AA 81-180

Spezifität: This antibody may also have a weak secondary cross-reaction with Mu-type opioid receptor, which is primarily expressed in the adrenal gland and testis. This is predicted based upon a 79 % non-contiguous sequence similarity.

Kreuzreaktivität: Human, Maus, Ratte

Homologie: Dog,Cow,Pig,Chicken,Rabbit,Guinea Pig

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human OPRD1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Referenzen für anti-OPRD1 Antikörper (ABIN2690091)

Wu, Li, Wu: "The effect of chronic intermittent hypoxia on respiratory sensitivity to morphine in rats." in: Sleep & breathing = Schlaf & Atmung, Vol. 21, Issue 1, pp. 227-233, (2017) (PubMed).

Details zu OPRD1

Target: OPRD1 (Opioid Receptor, delta 1 (OPRD1))

Andere Bezeichnung: Delta-type opioid receptor

Hintergrund:

Synonyms: OPRD, Delta-type opioid receptor, D-OR-1, DOR-1, OPRD1

Background: G-protein coupled receptor that functions as receptor for endogenous enkephalins and for a subset of other opioids. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling leads to the inhibition of adenylate cyclase activity. Inhibits neurotransmitter release by reducing calcium ion currents and increasing potassium ion conductance. Plays a role in the perception of pain and in opiate-mediated analgesia. Plays a role in developing analgesic tolerance to morphine.

Gen-ID: 4985

UniProt: P41143

Pathways: Protein targeting to Nucleus