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TACSTD2 Antikörper

Der Maus Monoklonal Anti-TACSTD2-Antikörper wurde für IHC und FACS validiert. Er ist geeignet, TACSTD2 in Proben von Human zu detektieren. Es sind 4+ Publikationen verfügbar.
Produktnummer ABIN2689944

Kurzübersicht für TACSTD2 Antikörper (ABIN2689944)

Target

Alle TACSTD2 Antikörper anzeigen
TACSTD2 (Tumor-Associated Calcium Signal Transducer 2 (TACSTD2))

Reaktivität

  • 99
  • 51
  • 19
  • 5
Human

Wirt

  • 62
  • 46
  • 3
  • 2
  • 1
Maus

Klonalität

  • 59
  • 55
Monoklonal

Konjugat

  • 49
  • 9
  • 5
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser TACSTD2 Antikörper ist unkonjugiert

Applikation

  • 71
  • 52
  • 33
  • 30
  • 26
  • 16
  • 13
  • 13
  • 9
  • 7
  • 4
  • 4
  • 3
  • 2
  • 2
  • 1
Immunohistochemistry (IHC), Flow Cytometry (FACS)

Klon

162
  • Marke

    BD Pharmingen™

    Produktmerkmale

    Trop-2/GA733-1 is a cell surface glycoprotein that was originally identified on human trophoblast and choriocarcinoma cell lines and has been shown to be expressed in most human carcinomas. Trop-2 has been cloned and shown to encode a type-1 transmembrane protein with a single transmembrane domain. Furthermore, research has shown Trop-2 to be involved in the transduction of an intracellular calcium signal, although the exact physiological mechanism has yet to be elucidated. Flow cytometric analysis of Trop-2. MCF7 cells (Human breast adenocarcinoma, ATCC HTB-22) were incubated with 0.25 μg of the Purified Mouse Anti-Human Trop-2 antibody (clone 162-46, shaded) or with a mouse IgG1 isotype control (Cat. No. 555746, unshaded) in BD Pharmingen™ Stain Buffer (Cat. No.554656) for 1 hr on ice. Cells were washed twice in Stain Buffer and incubated with 1 μg of a FITC Goat Anti-Mouse Ig secondary antibody (Cat. No.554001) in Stain Buffer for 1 hr on ice. Cells were washed twice and analyzed by flow cytometry.

    BD Pharmingen™ Purified Mouse Anti-Human Trop-2 - Purified - Clone 162-46 - Isotype Mouse IgG1, κ - Reactivity Hu - 0.1 mg

    Aufreinigung

    The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

    Immunogen

    Human BeWo (choriocarcinoma) Cell Line

    Isotyp

    IgG1 kappa
  • Applikationshinweise

    Optimal working dilution should be determined by the investigator.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Konzentration

    0.5 mg/mL

    Buffer

    Aqueous buffered solution containing ≤0.09 % sodium azide.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C

    Informationen zur Lagerung

    Store undiluted at 4°C.
  • Bobos, Kotoula, Kaloutsi, Karayannopoulou, Papadimitriou, Kostopoulos: "Aberrant CCND1 copies and cyclin D1 mRNA expression do not result in the production of functional cyclin D1 protein in anaplastic large cell lymphoma." in: Histology and histopathology, Vol. 24, Issue 8, pp. 1035-48, (2009) (PubMed).

    Ripani, Sacchetti, Corda, Alberti: "Human Trop-2 is a tumor-associated calcium signal transducer." in: International journal of cancer. Journal international du cancer, Vol. 76, Issue 5, pp. 671-6, (1998) (PubMed).

    Fornaro, DellArciprete, Stella, Bucci, Nutini, Capri, Alberti: "Cloning of the gene encoding Trop-2, a cell-surface glycoprotein expressed by human carcinomas." in: International journal of cancer. Journal international du cancer, Vol. 62, Issue 5, pp. 610-8, (1995) (PubMed).

    Lipinski, Parks, Rouse, Herzenberg: "Human trophoblast cell-surface antigens defined by monoclonal antibodies." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 78, Issue 8, pp. 5147-50, (1982) (PubMed).

  • Target

    TACSTD2 (Tumor-Associated Calcium Signal Transducer 2 (TACSTD2))

    Andere Bezeichnung

    Trop-2

    Hintergrund

    Synonyms: GA733-1
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