Zitiert in 3+ Publikationen.
Der Biotin-konjugierte Ratte Monoklonal anti-Ly76 Antikörper (Klon TER-119) (ABIN2689924) detektiert spezifisch Ly76 in FACS und IHC.
Dieser Antikörper reagiert spezifisch mit Proben aus Maus.
Kurzübersicht für Ly76 Antikörper (Biotin) (ABIN2689924)
Target
Ly76
(Lymphocyte Antigen 76 (Ly76))
Reaktivität
Maus
Wirt
Ratte
Klonalität
Monoklonal
Konjugat
Dieser Ly76 Antikörper ist konjugiert mit Biotin
Applikation
Flow Cytometry (FACS), Immunohistochemistry (IHC)
Klon
TER-119
Produktmerkmale
The TER-119 antibody reacts with a 52 kDa molecule associated with glycophorin A on cells of the erythroid lineage in embryonic yolk sac, fetal liver, newborn liver, adult bone marrow, adult peripheral blood, and adult lymphoid organs. The TER-119 antigen is expressed on erythroid cells from pro-erythroblast through mature erythrocyte stages, but not on cells with BFU-E or CFU-E activities. The TER-119 epitope is not detected on hematopoietic stem cells, lymphoid cells, myeloid cells, or erythroleukemia lines. The TER-119 mAb is a component of the "lineage cocktail" used in studies of hematopoietic progenitors to detect, or deplete cells committed to the hematopoietic lineages. This antibody is routinely tested by flow cytometric analysis. Other applications were tested during antibody development only or reported in the literature.
BD Pharmingen™ Biotin Rat Anti-Mouse TER-119/Erythroid Cells - Biotin - Clone TER-119 - Isotype Rat IgG2b, κ - Reactivity Ms - 0.5 mg
Aufreinigung
The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung
The antibody was conjugated with biotin under optimum conditions, and unreacted biotin was removed.
Lagerung
4 °C
Informationen zur Lagerung
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Kina, Ikuta, Takayama, Wada, Majumdar, Weissman, Katsura: "The monoclonal antibody TER-119 recognizes a molecule associated with glycophorin A and specifically marks the late stages of murine erythroid lineage." in: British journal of haematology, Vol. 109, Issue 2, pp. 280-7, (2000) (PubMed).
Kitajima, Kojima, Nakajima, Kondo, Hara, Miyajima, Takeuchi: "Definitive but not primitive hematopoiesis is impaired in jumonji mutant mice." in: Blood, Vol. 93, Issue 1, pp. 87-95, (1999) (PubMed).
Ikuta, Kina, MacNeil, Uchida, Peault, Chien, Weissman: "A developmental switch in thymic lymphocyte maturation potential occurs at the level of hematopoietic stem cells." in: Cell, Vol. 62, Issue 5, pp. 863-74, (1990) (PubMed).