Dieser Maus Monoklonal Antikörper detektiert spezifisch MHC, Class I in FACS, ELISA und IHC (fro). Es zeigt Reaktivität gegenüber Proben von Maus. Es wurde in 4+ Publikationen zitiert.
The SF1-1.1 antibody reacts with the α3 domain of the H-2K[d] MHC class I alloantigen. Reactivity with other haplotypes (e.g, b, j, k, p, q, s, v) has not been observed. It has been reported that plate-bound SF1-1.1 mAb moderately enhances the apoptotic response of thymocytes to plate-bound 145-2C11 mAb (anti-mouse CD3e, Cat. No. 557306/553058). This antibody is routinely tested by flow cytometric analysis. Other applications were tested during antibody development only or reported in the literature.
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung
The antibody was conjugated with biotin under optimum conditions, and unreacted biotin was removed.
Lagerung
4 °C
Informationen zur Lagerung
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Noun, Reboul, Abastado, Jaulin, Kourilsky, Pla: "Alloreactive monoclonal antibodies select Kd molecules with different peptide profiles." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 157, Issue 6, pp. 2455-61, (1996) (PubMed).
Zhao, Iwata: "Cross-linking of the TCR-CD3 complex with CD4, CD8 or LFA-1 induces an anti-apoptotic signal in thymocytes: the signal is canceled by FK506." in: International immunology, Vol. 7, Issue 9, pp. 1387-96, (1996) (PubMed).
Abastado, Casrouge, Kourilsky: "Differential role of conserved and polymorphic residues of the binding groove of MHC class I molecules in the selection of peptides." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 151, Issue 7, pp. 3569-75, (1993) (PubMed).
Matsumoto, Setoyama, Umesaki: "Differential induction of major histocompatibility complex molecules on mouse intestine by bacterial colonization." in: Gastroenterology, Vol. 103, Issue 6, pp. 1777-82, (1993) (PubMed).