MHC, Class I Antikörper (Biotin)
Kurzübersicht für MHC, Class I Antikörper (Biotin) (ABIN2689544)
Target
Alle MHC, Class I Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Marke
- BD Pharmingen™
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Produktmerkmale
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The SF1-1.1 antibody reacts with the α3 domain of the H-2K[d] MHC class I alloantigen. Reactivity with other haplotypes (e.g, b, j, k, p, q, s, v) has not been observed. It has been reported that plate-bound SF1-1.1 mAb moderately enhances the apoptotic response of thymocytes to plate-bound 145-2C11 mAb (anti-mouse CD3e, Cat. No. 557306/553058). This antibody is routinely tested by flow cytometric analysis. Other applications were tested during antibody development only or reported in the literature.
BD Pharmingen™ Biotin Mouse Anti-Mouse H-2K[d] - Biotin - Clone SF1-1.1 - Isotype Mouse IgG2a, κ - Reactivity Ms - 0.5 mg -
Aufreinigung
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
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Immunogen
- BALB/c mouse cells
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Isotyp
- IgG2a kappa
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 0.5 mg/mL
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Buffer
- Aqueous buffered solution containing ≤0.09 % sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- The antibody was conjugated with biotin under optimum conditions, and unreacted biotin was removed.
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Lagerung
- 4 °C
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Informationen zur Lagerung
- Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
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: "Alloreactive monoclonal antibodies select Kd molecules with different peptide profiles." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 157, Issue 6, pp. 2455-61, (1996) (PubMed).
: "Cross-linking of the TCR-CD3 complex with CD4, CD8 or LFA-1 induces an anti-apoptotic signal in thymocytes: the signal is canceled by FK506." in: International immunology, Vol. 7, Issue 9, pp. 1387-96, (1996) (PubMed).
: "Differential role of conserved and polymorphic residues of the binding groove of MHC class I molecules in the selection of peptides." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 151, Issue 7, pp. 3569-75, (1993) (PubMed).
: "Differential induction of major histocompatibility complex molecules on mouse intestine by bacterial colonization." in: Gastroenterology, Vol. 103, Issue 6, pp. 1777-82, (1993) (PubMed).
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: "Alloreactive monoclonal antibodies select Kd molecules with different peptide profiles." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 157, Issue 6, pp. 2455-61, (1996) (PubMed).
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- MHC, Class I
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Andere Bezeichnung
- H-2K[d]
Target
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