CD58 Antikörper

Produktnummer ABIN2689345

Produktdetails anti-CD58 Antikörper

Target: CD58

Reaktivität: Human, Hund

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD58 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS)

Marke: BD Pharmingen™

Produktmerkmale: Reacts with a 60-70 kDa membrane glycoprotein member of the immunoglobulin superfamily. CD58, also referred to as the lymphocyte function-associated antigen-3 (LFA-3), has a wide tissue distribution, being expressed on both hematopoietic and non-hematopoietic cells, including endothelial cells and fibroblasts. There are two isoforms of CD58: a glycosylphosphatidylinositol (GPI)-linked formed and a transmembrane form. Both isoforms may be expressed in the same cell type. Erythrocytes, however, only have the GPI-linked isoform. CD58 interacts with CD2 during cell adhesion. This binding can enhance antigen-specific T-cell activation. This antibody is routinely tested by flow cytometric analysis. Other applications were tested during antibody development only or reported in the literature. Profile of peripheral blood lymphocytes analyzed on a FACScan

BD Pharmingen™ Purified Mouse Anti-Human CD58 - Purified - Clone 1C3 (also known as AICD58) - Isotype Mouse IgG2a, κ - Reactivity Hu, Dog - 0.1 mg

Aufreinigung: The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

Klon: 1C3

Isotyp: IgG2a kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Aqueous buffered solution containing ≤0.09 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store undiluted at 4°C.

Referenzen für anti-CD58 Antikörper (ABIN2689345)

Dengler, Hoffmann, Knolle, Albert-Wolf, Roux, Wallich, Meuer: "Structural and functional epitopes of the human adhesion receptor CD58 (LFA-3)." in: European journal of immunology, Vol. 22, Issue 11, pp. 2809-17, (1992) (PubMed).

Details zu CD58

Target: CD58

Andere Bezeichnung: CD58 (CD58 Produkte)

Synonyme: LFA-3 antikoerper, LFA3 antikoerper, ag3 antikoerper, CD58 molecule antikoerper, CD58 antikoerper

Hintergrund: Synonyms: LFA-3