ITGA5 Antikörper
Kurzübersicht für ITGA5 Antikörper (ABIN2689314)
Target
Alle ITGA5 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Produktmerkmale
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Reacts with the α5 integrin, a dimer of 135/25 kDa, that associates with β1 integrin (CD29) to form VLA-5, a well-established fibronectin receptor that is expressed on many cell types, including fibroblasts, endothelial cells, epithelial cells, platelets, peripheral T cells, the myeloid cell line U937, K562 and some melanoma cell lines. This clone inhibits α5β1/ligand binding, and is useful for studies of the expression and function of this integrin. This antibody is routinely tested by flow cytometric analysis. Other applications were tested during antibody development only or reported in the literature. Profile of K562 cells analyzed on a FACScan
BD Pharmingen™ Purified Mouse Anti-Human CD49e - Purified - Clone IIA1 - Isotype Mouse IgG1, κ - Reactivity Hu, Rab - 0.1 mg -
Aufreinigung
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
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Isotyp
- IgG1 kappa
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 0.5 mg/mL
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Buffer
- Aqueous buffered solution containing ≤0.09 % sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Informationen zur Lagerung
- Store undiluted at 4°C.
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: "Bacterial internalization mediated by beta 1 chain integrins is determined by ligand affinity and receptor density." in: The EMBO journal, Vol. 12, Issue 5, pp. 1887-95, (1993) (PubMed).
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- ITGA5 (Integrin, alpha 5 (ITGA5))
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Andere Bezeichnung
- CD49e
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Hintergrund
- Synonyms: Integrin α5 Chain
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Pathways
- Integrin Complex
Target
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