Der Maus Monoklonal Anti-ITGA5-Antikörper wurde für FACS validiert. Er ist geeignet, ITGA5 in Proben von Human und Kaninchen zu detektieren. Es ist 1 Publikation verfügbar.
Reacts with the α5 integrin, a dimer of 135/25 kDa, that associates with β1 integrin (CD29) to form VLA-5, a well-established fibronectin receptor that is expressed on many cell types, including fibroblasts, endothelial cells, epithelial cells, platelets, peripheral T cells, the myeloid cell line U937, K562 and some melanoma cell lines. This clone inhibits α5β1/ligand binding, and is useful for studies of the expression and function of this integrin. This antibody is routinely tested by flow cytometric analysis. Other applications were tested during antibody development only or reported in the literature. Profile of K562 cells analyzed on a FACScan
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C
Informationen zur Lagerung
Store undiluted at 4°C.
Tran Van Nhieu, Isberg: "Bacterial internalization mediated by beta 1 chain integrins is determined by ligand affinity and receptor density." in: The EMBO journal, Vol. 12, Issue 5, pp. 1887-95, (1993) (PubMed).