ITGA5 Antikörper

Produktnummer ABIN2689313

Dieses Maus Monoklonal-Antikörper erkennt spezifisch ITGA5 in FACS. Er zeigt eine Reaktivität gegenüber Human und Schwein und wurde in 2+ Publikationen erwähnt.

Kurzübersicht für ITGA5 Antikörper (ABIN2689313)

Target: ITGA5 (Integrin, alpha 5 (ITGA5))

Reaktivität: Human, Schwein

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser ITGA5 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS)

Klon: VC5

Produktdetails anti-ITGA5 Antikörper

Marke: BD Pharmingen™

Produktmerkmale: Reacts with the α5 integrin, a dimer of 135/25 kDa, that associates with β1 integrin (CD29) to form VLA-5, a well-established fibronectin receptor that is expressed on many cell types, including fibroblasts, endothelial cells, epithelial cells, platelets, peripheral T cells, the myeloid cell line U937, K562 and some melanoma cell lines. This clone does not inhibit α5β1/ligand binding. This antibody is routinely tested by flow cytometric analysis. Other applications were tested during antibody development only or reported in the literature. Profile of peripheral blood lymphocytes analyzed on a FACScan

BD Pharmingen™ Purified Mouse Anti-Human CD49e - Purified - Clone VC5 - Isotype Mouse IgG1, κ - Reactivity Hu, Pig - 0.1 mg

Aufreinigung: The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Aqueous buffered solution containing ≤0.09 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store undiluted at 4°C.

Referenzen für anti-ITGA5 Antikörper (ABIN2689313)

Tran Van Nhieu, Isberg: "Bacterial internalization mediated by beta 1 chain integrins is determined by ligand affinity and receptor density." in: The EMBO journal, Vol. 12, Issue 5, pp. 1887-95, (1993) (PubMed).

Van Nhieu, Isberg: "The Yersinia pseudotuberculosis invasin protein and human fibronectin bind to mutually exclusive sites on the alpha 5 beta 1 integrin receptor." in: The Journal of biological chemistry, Vol. 266, Issue 36, pp. 24367-75, (1992) (PubMed).

Details zu ITGA5

Target: ITGA5 (Integrin, alpha 5 (ITGA5))

Andere Bezeichnung: CD49e

Hintergrund: Synonyms: Integrin α5 chain

Pathways: Integrin Complex