Fc gamma RII (CD32) Antikörper

Produktnummer ABIN2689189

Zitiert in 1 Publikation. Der Maus Monoklonal anti-Fc gamma RII Antikörper (Klon FLI8-26) (ABIN2689189) detektiert spezifisch Fc gamma RII in FACS. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Rhesusaffen, Pavian und Cynomolgus.

Kurzübersicht für Fc gamma RII (CD32) Antikörper (ABIN2689189)

Target: Fc gamma RII (CD32)

Reaktivität: Human, Rhesusaffen, Pavian, Cynomolgus

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Unkonjugiert

Applikation: Flow Cytometry (FACS)

Klon: FLI8-26

Produktdetails

Produktmerkmale: Reacts with the 40 kDa type I membrane glycoprotein, FcγRII, the low affinity receptor for aggregated IgG expressed on B cells, monocytes, granulocytes, and platelets. CD32 mediates endocytosis, cytotoxicity, platelet activation and immunomodulation. This antibody is routinely tested by flow cytometric analysis. Other applications were tested during antibody development only or reported in the literature. Profile of peripheral blood lymphocytes analyzed on a FACScan Profile of peripheral blood monocytes analyzed on a FACScan Profile of peripheral blood granulocytes analyzed on a FACScan

BD Pharmingen™ Purified Mouse Anti-Human CD32 - Purified - Clone FLI8.26 (2003) - Isotype Mouse IgG2b, κ - Reactivity Hu, Bab, Cyno, Rhe - 0.1 mg

Aufreinigung: The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

Isotyp: IgG2b kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Aqueous buffered solution containing ≤0.09 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store undiluted at 4°C.

Referenzen

Tomiyama, Kunicki, Zipf, Ford, Aster: "Response of human platelets to activating monoclonal antibodies: importance of Fc gamma RII (CD32) phenotype and level of expression." in: Blood, Vol. 80, Issue 9, pp. 2261-8, (1992) (PubMed).

Antigendetails

Target: Fc gamma RII (CD32)

Andere Bezeichnung: CD32

Hintergrund: Synonyms: FcγRII