Reacts with an 80-90 kDa, mucin-like molecule present on CD34+ cells during the early stages of B cell, erythroid cell and myelomonocytic cell development. It is also expressed on epithelial cells, peripheral blood monocytes and weakly on lymphocytes. Mucin-like molecules are a new family of glycoproteins present in tissues of the hematopoietic system. They are highly glycosylated polypeptides, containing predominantly O-linked carbohydrate side chains. Reports suggest that CD164 may play a role in hematopoiesis by facilitating the adhesion of CD34+ cells to bone marrow stroma. This antibody is routinely tested by flow cytrometric analysis. Other applications were tested at BD Bioscience Pharmingen during antibody development only or reported in the literature. Profile of peripheral blood monocytes analyzed by flow cytometry. Second step staining with Cat. No. 555988
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Store undiluted at 4°C.
Watt, Bühring, Rappold, Chan, Lee-Prudhoe, Jones, Zannettino, Simmons, Doyonnas, Sheer, Butler: "CD164, a novel sialomucin on CD34(+) and erythroid subsets, is located on human chromosome 6q21." in: Blood, Vol. 92, Issue 3, pp. 849-66, (1998) (PubMed).