BST1 Antikörper

Produktnummer ABIN2688997

Dieses Anti-BST1-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von BST1 in FACS, IP, IF und IAC. Geeignet für Maus. Dieses Primary Antibody wurde in 6+ Publikationen zitiert.

Kurzübersicht für BST1 Antikörper (ABIN2688997)

Target: BST1 (Bone Marrow Stromal Cell Antigen 1 (BST1))

Reaktivität: Maus

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser BST1 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Immunoprecipitation (IP), Immunofluorescence (IF), Immunoaffinity Chromatography (IAC)

Klon: BP

Produktdetails anti-BST1 Antikörper

Marke: BD Pharmingen™

Produktmerkmale: The BP-3 antibody reacts with CD157, also known as the BP-3 alloantigen or Bone marrow STromal cell antigen-1 (BST-1), found in a variety of common laboratory strains of mice (AKR, BALB/c, CBA/N, C3H/HeJ, C57BL/6, DBA/2, NZB, C.B-17, SJL and Swiss, but not A/J). CD157 is a differentially glycosylated GPI-linked cell-surface glycoprotein with a core protein of 32 kDa and differing patterns of glycosylation in different types of cells. It is a member, along with CD38, of a family of genetically-related ectoenzymes. The BP-3 alloantigen is expressed on the B lineage from the earliest detectable progenitors to circulating immature B lymphocytes, on immature thymocytes up to the expression of the T-cell receptor, on circulating neutrophils, peritoneal macrophages, on subpopulations of stromal cells in peripheral lymphoid organs (but not in bone marrow or thymus), on intestinal epithelial cells, and in the lumen of kidney-collecting tubules. The distribution of CD157 antigen on leukocytes and stromal cells of lymphoid organs suggests that it may be involved in leukocyte-stroma interactions which support the development, migration, and/or responses of leukocyte populations.

BD Pharmingen™ Purified Mouse Anti-Mouse CD157 - Purified - Clone BP-3 - Isotype Mouse IgG2b, κ - Reactivity Ms - 0.1 mg

Aufreinigung: The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

Immunogen: Mouse pre-B cell line

Isotyp: IgG2b kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Aqueous buffered solution containing ≤0.09 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store undiluted at 4°C.

Referenzen für anti-BST1 Antikörper (ABIN2688997)

Ngo, Korner, Gunn, Schmidt, Riminton, Cooper, Browning, Sedgwick, Cyster: "Lymphotoxin alpha/beta and tumor necrosis factor are required for stromal cell expression of homing chemokines in B and T cell areas of the spleen." in: The Journal of experimental medicine, Vol. 189, Issue 2, pp. 403-12, (1999) (PubMed).

Itoh, Ishihara, Hiroi, Lee, Maeda, Iijima, Yanagita, Kiyono, Hirano: "Deletion of bone marrow stromal cell antigen-1 (CD157) gene impaired systemic thymus independent-2 antigen-induced IgG3 and mucosal TD antigen-elicited IgA responses." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 161, Issue 8, pp. 3974-83, (1998) (PubMed).

Dong, Willerford, Alt, Cooper: "Genomic organization and chromosomal localization of the mouse Bp3 gene, a member of the CD38/ADP-ribosyl cyclase family." in: Immunogenetics, Vol. 45, Issue 1, pp. 35-43, (1996) (PubMed).

Dong, Wang, Neame, Cooper: "The murine BP-3 gene encodes a relative of the CD38/NAD glycohydrolase family." in: International immunology, Vol. 6, Issue 9, pp. 1353-60, (1995) (PubMed).

McNagny, Bucy, Cooper: "Reticular cells in peripheral lymphoid tissues express the phosphatidylinositol-linked BP-3 antigen." in: European journal of immunology, Vol. 21, Issue 2, pp. 509-15, (1991) (PubMed).

McNagny, Cazenave, Cooper: "BP-3 alloantigen. A cell surface glycoprotein that marks early B lineage cells and mature myeloid lineage cells in mice." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 141, Issue 8, pp. 2551-6, (1988) (PubMed).

Details zu BST1

Target: BST1 (Bone Marrow Stromal Cell Antigen 1 (BST1))

Andere Bezeichnung: CD157

Hintergrund: Synonyms: BP-3 Alloantigen