Menin Antikörper (AA 392-554)

Produktnummer ABIN2682998

Dieses Anti-Menin-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von Menin in ELISA, IHC und FACS. Geeignet für Human.

Kurzübersicht für Menin Antikörper (AA 392-554) (ABIN2682998)

Target: Menin (MEN1) (Multiple Endocrine Neoplasia 1 (MEN1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Menin Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)

Klon: 7D3E10

Produktdetails anti-Menin Antikörper

Bindungsspezifität: AA 392-554

Verwendungszweck: MEN1 Antibody

Aufreinigung: Purified antibody

Immunogen: Purified recombinant fragment of human MEN1 (AA: 392-554) expressed in E. Coli.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise:

ELISA: 1/10000

FCM: 1/200 - 1/400

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Details zu Menin

Target: Menin (MEN1) (Multiple Endocrine Neoplasia 1 (MEN1))

Andere Bezeichnung: MEN1

Hintergrund: This gene encodes menin, a putative tumor suppressor associated with a syndrome known as multiple endocrine neoplasia type 1. In vitro studies have shown menin is localized to the nucleus, possesses two functional nuclear localization signals, and inhibits transcriptional activation by JunD, however, the function of this protein is not known. Two messages have been detected on northern blots but the larger message has not been characterized. Alternative splicing results in multiple transcript variants.

Molekulargewicht: 68 kDa

Gen-ID: 4221

UniProt: O00255

Pathways: Chromatin Binding, Positive Regulation of Endopeptidase Activity