PIWIL2 Antikörper

Produktnummer ABIN2668966

Es gibt 1 Publikation für dieses Produkt. Der Maus Monoklonal anti-PIWIL2 Antikörper wird verwendet zum Nachweis von PIWIL2 in Proben von Maus. Er wurde validiert für WB, ICC, IF und IP.

Kurzübersicht für PIWIL2 Antikörper (ABIN2668966)

Target: PIWIL2 (Piwi-Like 2 (PIWIL2))

Reaktivität: Maus

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser PIWIL2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunoprecipitation (IP)

Klon: 17-8

Produktdetails anti-PIWIL2 Antikörper

Verwendungszweck: Mili / PiwiL2 antibody (mAb) (Clone 17.8)

Aufreinigung: Protein G Chromatography

Immunogen: This Mili / PiwiL2 antibody was raised against full-length recombinant mouse MILI / PIWIL2 protein.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: This antibody is also available as an AbFlex engineered recombinant antibody. For details on the corresponding AbFlex Recombinant Antibody, see Catalog No. 91253.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 μg/μL

Buffer: Purified IgG in PBS with 30 % glycerol and 0.035 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage

Lagerung: -20 °C

Informationen zur Lagerung: Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Haltbarkeit: 24 months

Referenzen für anti-PIWIL2 Antikörper (ABIN2668966)

Kirino, Kim, de Planell-Saguer, Khandros, Chiorean, Klein, Rigoutsos, Jongens, Mourelatos: "Arginine methylation of Piwi proteins catalysed by dPRMT5 is required for Ago3 and Aub stability." in: Nature cell biology, Vol. 11, Issue 5, pp. 652-8, (2009) (PubMed).

Details zu PIWIL2

Target: PIWIL2 (Piwi-Like 2 (PIWIL2))

Andere Bezeichnung: Mili / PiwiL2

Hintergrund: Mili / PiwiL2 is a member of the PIWI/AGO subfamily of RNA-binding proteins. Mili / PiwiL2 contains a Piwi and an AGO domain and binds a class of RNA called piwi-interacting RNA (piRNA), which are 24 to 30 nucleotides in length and are derived primarily derived from transposons and other repeated sequence elements. Mili / PiwiL2 is required for methylation and inactivation of retrotransposons. Mice deficient in Mili / PiwiL2 are sterile, as it is also required for spermatogenesis. It also positively regulates translation, and is required for germ line stem cell division and differentiation.

Molekulargewicht: 97 kDa

Gen-ID: 57746

NCBI Accession: NP_001129193

Pathways: Stem Cell Maintenance