FOXP1 Antikörper (AA 495-578)

Produktnummer ABIN2668950

Dieser Maus Monoklonal Antikörper detektiert spezifisch FOXP1 in WB, ChIP, SSA und ChIP-seq. Es zeigt Reaktivität gegenüber Proben von Maus. Es wurde in 2+ Publikationen zitiert.

Kurzübersicht für FOXP1 Antikörper (AA 495-578) (ABIN2668950)

Target: FOXP1 (Forkhead Box P1 (FOXP1))

Reaktivität: Maus

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser FOXP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Chromatin Immunoprecipitation (ChIP), Supershift Assay (SSA), ChIP DNA-Sequencing (ChIP-seq)

Klon: 1G1

Produktdetails anti-FOXP1 Antikörper

Bindungsspezifität: AA 495-578

Verwendungszweck: FOXP1 antibody (mAb) (Clone 1G1)

Aufreinigung: Protein A Chromatography

Immunogen: This FOXP1 antibody was raised against a recombinant protein corresponding to amino acids 495-578 of mouse FOXP1. This antibody detects three isoforms.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 μg/μL

Buffer: Purified IgG in PBS with 30 % glycerol and 0.035 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage

Lagerung: -20 °C

Informationen zur Lagerung: Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Haltbarkeit: 24 months

Referenzen für anti-FOXP1 Antikörper (ABIN2668950)

Hu, Wang, Borde, Nardone, Maika, Allred, Tucker, Rao: "Foxp1 is an essential transcriptional regulator of B cell development." in: Nature immunology, Vol. 7, Issue 8, pp. 819-26, (2006) (PubMed).

Wang, Lin, Li, Tucker: "Multiple domains define the expression and regulatory properties of Foxp1 forkhead transcriptional repressors." in: The Journal of biological chemistry, Vol. 278, Issue 27, pp. 24259-68, (2003) (PubMed).

Details zu FOXP1

Target: FOXP1 (Forkhead Box P1 (FOXP1))

Andere Bezeichnung: FOXP1

Hintergrund: FOXP1 (forkhead box P1) is a transcriptional repressor and belongs to subfamily P of the forkhead box (FOX) transcription factor family. It plays an important role in the specification and differentiation of lung epithelium. Can act with CTBP1 to synergistically repress transcription but CTPBP1 is not essential. Essential transcriptional regulator of B-cell development (By similarity).

Molekulargewicht: 95, 70 & 50 kDa

Gen-ID: 108655

NCBI Accession: NP_444432

Pathways: Chromatin Binding, Regulation of Muscle Cell Differentiation, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response