STAT5 A/B Antikörper (pTyr694, pTyr699)

Produktnummer ABIN2668940

Zitiert in 1 Publikation. Der Kaninchen Polyklonal anti-STAT5 A/B Antikörper (ABIN2668940) detektiert spezifisch STAT5 A/B in WB und DB. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für STAT5 A/B Antikörper (pTyr694, pTyr699) (ABIN2668940)

Target: STAT5 A/B

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser STAT5 A/B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Dot Blot (DB)

Produktdetails anti-STAT5 A/B Antikörper

Bindungsspezifität: pTyr694, pTyr699

Verwendungszweck: STAT5A/B phospho Tyr694/Tyr699 antibody (pAb)

Aufreinigung: Affinity Purified

Immunogen: This STAT5A/B phospho Tyr694/Tyr699 antibody was raised against a peptide containing phospho Tyr694 of human STAT5A. Human STAT5B shares the identical sequence surrounding Tyr699.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500 - 1:2,000 dilution

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified IgG in 70 mM Tris ( pH 8), 105 mM NaCl, 31 mM glycine, 0.07 mM EDTA, 30 % glycerol and 0.035 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage

Lagerung: -20 °C

Informationen zur Lagerung: Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Haltbarkeit: 24 months

Referenzen für anti-STAT5 A/B Antikörper (ABIN2668940)

Basu, Wu, Kopchick: "Targeting growth hormone receptor in human melanoma cells attenuates tumor progression and epithelial mesenchymal transition via suppression of multiple oncogenic pathways." in: Oncotarget, Vol. 8, Issue 13, pp. 21579-21598, (2017) (PubMed).

Details zu STAT5 A/B

Target: STAT5 A/B

Andere Bezeichnung: STAT5A/B

Hintergrund: STAT5A/B (signal transducer and activator of transcription 5) is a member of the STAT family of transcription factors. STATs undergo serine and tyrosine phosphorylation in response to growth factor or cytokine signaling. This phosphorylation results in dimerization and translocation of STAT proteins to the nucleus. The STAT5 protein is expressed in most cell types and is activated by multiple cytokines and growth factors including: IFNA1, IL-10, IL-6, IL-11, IL-12, IL-2, EGF, among others. Other members of the STAT family include STAT1a, STAT2, STAT3, STAT4, STAT5A, STAT5B and STAT6.

Molekulargewicht: 92 kDa

Gen-ID: 6776