ZBTB16 Antikörper

Produktnummer ABIN2668927

Es sind 3+ Publikationen für dieses Produkt verfügbar. Der Maus Monoklonal anti-ZBTB16 Antikörper wird verwendet zum Nachweis von ZBTB16 in Proben von Human und Maus. Er wurde validiert für WB, IF, ICC, IP und ChIP.

Kurzübersicht für ZBTB16 Antikörper (ABIN2668927)

Target: ZBTB16 (Zinc Finger and BTB Domain Containing 16 (ZBTB16))

Reaktivität: Human, Maus

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser ZBTB16 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunoprecipitation (IP), Chromatin Immunoprecipitation (ChIP)

Klon: 2A9

Produktdetails anti-ZBTB16 Antikörper

Verwendungszweck: PLZF antibody (mAb) (Clone 2A9)

Aufreinigung: Protein G Chromatography

Immunogen: This PLZF antibody was raised against a recombinant protein corresponding to full-length mouse PLZF with a GST-Tag.

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 μg/μL

Buffer: PBS pH 7.5 containing 30 % glycerol and 0.035 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage

Lagerung: -20 °C

Informationen zur Lagerung: Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Haltbarkeit: 24 months

Referenzen für anti-ZBTB16 Antikörper (ABIN2668927)

Felli, Errico, Pedini, Petrini, Puglisi, Bellenghi, Boe, Felicetti, Mattia, De Feo, Bottero, Tripodo, Carè: "AP2α controls the dynamic balance between miR-126&126* and miR-221&222 during melanoma progression." in: Oncogene, Vol. 35, Issue 23, pp. 3016-26, (2016) (PubMed).

Chapman, Medrano, Chaudhary, Hamra: "NRG1 and KITL Signal Downstream of Retinoic Acid in the Germline to Support Soma-Free Syncytial Growth of Differentiating Spermatogonia." in: Cell death discovery, Vol. 1, (2015) (PubMed).

Koken, Reid, Quignon, Chelbi-Alix, Davies, Kabarowski, Zhu, Dong, Chen, Chen, Tan, Licht, Waxman, de Thé, Zelent: "Leukemia-associated retinoic acid receptor alpha fusion partners, PML and PLZF, heterodimerize and colocalize to nuclear bodies." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 94, Issue 19, pp. 10255-60, (1997) (PubMed).

Details zu ZBTB16

Target: ZBTB16 (Zinc Finger and BTB Domain Containing 16 (ZBTB16))

Andere Bezeichnung: PLZF

Hintergrund: PLZF (Promyelocytic Leukemia Zinc-Finger protein) is a member of the POK (POZ and Krüppel) family of transcriptional repressors. PLZF is expressed in early, but not differentiated, hematopoietic cells, and is required for spermatogonial stem cell maintenance. In addition, PLZF regulates genes involved in cellular proliferation and differentiation (cyclin A2, Myc and Hox genes) and targeted deletion of PLZF in mice results in limb and axial skeleton and limb deformations.

Molekulargewicht: 90 kDa

Gen-ID: 235320

NCBI Accession: NP_001028496

Pathways: Positive Regulation of fat Cell Differentiation