MTF2 Antikörper

Produktnummer ABIN2668833

Dieser Maus Monoklonal Antikörper detektiert spezifisch MTF2 in WB. Es zeigt Reaktivität gegenüber Proben von Human.Es wurde in 1 Publikation zitiert.

Kurzübersicht für MTF2 Antikörper (ABIN2668833)

Target: MTF2 (Metal Response Element Binding Transcription Factor 2 (MTF2))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser MTF2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: 3A9

Produktdetails anti-MTF2 Antikörper

Verwendungszweck: PCL2 antibody (mAb) (Clone 3A9)

Aufreinigung: Protein G Chromatography

Immunogen: This PCL2 antibody was raised against a recombinant protein corresponding to amino acids 103 - 327 of mouse PCL2.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 μg/μL

Buffer: Purified IgG in PBS with 30 % glycerol and 0.035 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage

Lagerung: -20 °C

Informationen zur Lagerung: Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Haltbarkeit: 24 months

Referenzen für anti-MTF2 Antikörper (ABIN2668833)

Li, Isono, Yamada, Endo, Endoh, Shinga, Mizutani-Koseki, Otte, Casanova, Kitamura, Kamijo, Sharif, Ohara, Toyada, Bernstein, Brockdorff, Koseki: "Mammalian polycomb-like Pcl2/Mtf2 is a novel regulatory component of PRC2 that can differentially modulate polycomb activity both at the Hox gene cluster and at Cdkn2a genes." in: Molecular and cellular biology, Vol. 31, Issue 2, pp. 351-64, (2010) (PubMed).

Details zu MTF2

Target: MTF2 (Metal Response Element Binding Transcription Factor 2 (MTF2))

Andere Bezeichnung: PCL2

Hintergrund: PCL2 (Polycomb-like 2, MTF2, M96) is a member of the Polycomb PRC2 protein complex and is important in cell fate decisions and may play a role in recruitment of PRC2 to target genes and histone methylation. PCL2 regulates gene expression patterns controlling self-renewal and commitment in embryonic stem cells and plays a critical role in ESC differentiation and self-renewal. PCL2 contains two PHD fingers.

Molekulargewicht: 70 kDa

Gen-ID: 17765

NCBI Accession: NP_038855

Pathways: Stem Cell Maintenance