IKZF3 Antikörper (N-Term)

Produktnummer ABIN2668825

Es gibt 1 Publikation für dieses Produkt. Der Maus Monoklonal anti-IKZF3 Antikörper wird verwendet zum Nachweis von IKZF3 in Proben von Maus. Er wurde validiert für WB und ChIP.

Kurzübersicht für IKZF3 Antikörper (N-Term) (ABIN2668825)

Target: IKZF3 (IKAROS Family Zinc Finger 3 (Aiolos) (IKZF3))

Reaktivität: Maus

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser IKZF3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Chromatin Immunoprecipitation (ChIP)

Klon: 8B2

Produktdetails anti-IKZF3 Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: Aiolos antibody (mAb) (Clone 8B2)

Aufreinigung: Protein G Chromatography

Immunogen: This Aiolos antibody was raised against the N-terminal half of mouse Aiolos protein.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 μg/μL

Buffer: Purified IgG in 70 mM Tris ( pH 8), 105 mM NaCl, 31 mM glycine, 0.07 mM EDTA, 30 % glycerol and 0.035 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage

Lagerung: -20 °C

Informationen zur Lagerung: Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Haltbarkeit: 24 months

Referenzen für anti-IKZF3 Antikörper (ABIN2668825)

Thompson, Cobb, Sabbattini, Meixlsperger, Parelho, Liberg, Taylor, Dillon, Georgopoulos, Jumaa, Smale, Fisher, Merkenschlager: "Ikaros DNA-binding proteins as integral components of B cell developmental-stage-specific regulatory circuits." in: Immunity, Vol. 26, Issue 3, pp. 335-44, (2007) (PubMed).

Details zu IKZF3

Target: IKZF3 (IKAROS Family Zinc Finger 3 (Aiolos) (IKZF3))

Andere Bezeichnung: Aiolos

Hintergrund: Aiolos (also known as IKZF3, Ikaros family zinc finger 3 and ZNFN1A3) belongs to a family of zinc-finger proteins that also include Ikaros and Helios. Aiolos is a transcription factor that is important in the regulation of lymphocyte proliferation and differentiation, which is preferentially expressed in peripheral blood leukocytes, spleen and thymus tissue. Both Ikaros and Aiolos can also participate in chromatin remodeling.

Molekulargewicht: 70 kDa

Gen-ID: 22780

NCBI Accession: NP_035901