MEIS1/MEIS2/MEIS3 (AA 50-390) Antikörper

Produktnummer ABIN2668724

Zitiert in 3+ Publikationen. Der Maus Monoklonal anti-MEIS1/MEIS2/MEIS3 Antikörper (Klon 9-2-7) (ABIN2668724) detektiert spezifisch MEIS1/MEIS2/MEIS3 in ICC und IF. Dieser Antikörper reagiert spezifisch mit Proben aus Human und Maus.

Kurzübersicht für MEIS1/MEIS2/MEIS3 (AA 50-390) Antikörper (ABIN2668724)

Target: MEIS1/MEIS2/MEIS3

Reaktivität: Human, Maus

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Unkonjugiert

Applikation: Immunocytochemistry (ICC), Immunofluorescence (IF)

Klon: 9-2-7

Produktdetails

Bindungsspezifität: AA 50-390

Verwendungszweck: MEIS 1/2/3 antibody (mAb) (Clone 9.2.7)

Aufreinigung: Protein A Chromatography

Immunogen: This MEIS antibody was raised against a recombinant protein corresponding to amino acids amino acids 50-390 mouse MEIS1.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ICC/IF: 0.5 μg/mL dilution This antibody is also available as an AbFlex engineered recombinant antibody. For details on the corresponding AbFlex Recombinant Antibody, see Catalog No. 91259.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 μg/μL

Buffer: Purified IgG in PBS with 30 % glycerol and 0.035 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage

Lagerung: -20 °C

Informationen zur Lagerung: Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Haltbarkeit: 24 months

Referenzen

Przepiorski, Vanichapol, Espiritu, Crunk, Parasky, McDaniels, Emlet, Salisbury, Happ, Vernetti, MacDonald, Kellum, Kleyman, Baty, Davidson, Hukriede: "Modeling oxidative injury response in human kidney organoids." in: Stem cell research & therapy, Vol. 13, Issue 1, pp. 76, (2022) (PubMed).

Hilliard, Yao, El-Dahr: "Mdm2 is required for maintenance of the nephrogenic niche." in: Developmental biology, Vol. 387, Issue 1, pp. 1-14, (2014) (PubMed).

Shim, Kim, Shin, Kim, Park: "Regulation of EphA8 gene expression by TALE homeobox transcription factors during development of the mesencephalon." in: Molecular and cellular biology, Vol. 27, Issue 5, pp. 1614-30, (2007) (PubMed).

Antigendetails

Target: MEIS1/MEIS2/MEIS3

Andere Bezeichnung: MEIS 1/2/3

Hintergrund: The MEIS family or proteins (Myeloid Ecotropic viral Integration Site homologues) encode proteins that function as cofactors for the Homeobox (HOX) proteins. Homeobox genes play a crucial role in normal development. In addition, several homeoproteins are involved in neoplasia. MEIS and a functionally related protein Pbx belong to the TALE (Three Amino acid Loop Extension) homeodomain superfamily of proteins. The role of MEIS proteins in the regulation of transcription is as yet unclear.

Molekulargewicht: 54-66 kDa

Gen-ID: 4211

NCBI Accession: NP_034919