Retinoic Acid Receptor beta Antikörper (AA 413-448)

Produktnummer ABIN2668691

Zitiert in 2+ Publikationen. Der Maus Monoklonal anti-Retinoic Acid Receptor beta Antikörper (Klon 8B-10B2) (ABIN2668691) detektiert spezifisch Retinoic Acid Receptor beta in WB, IHC und SSA. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für Retinoic Acid Receptor beta Antikörper (AA 413-448) (ABIN2668691)

Target: Retinoic Acid Receptor beta (RARB) (Retinoic Acid Receptor, beta (RARB))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Retinoic Acid Receptor beta Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Supershift Assay (SSA)

Klon: 8B-10B2

Produktdetails anti-Retinoic Acid Receptor beta Antikörper

Bindungsspezifität: AA 413-448

Verwendungszweck: RAR-beta antibody (mAb) (Clone 8B-10B2)

Aufreinigung: Protein G Chromatography

Immunogen: This RAR-beta antibody was raised against amino acids 413-448 of human RAR-beta.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 μg/μL

Buffer: Purified IgG in 70 mM Tris ( pH 8), 105 mM NaCl, 31 mM glycine, 0.07 mM EDTA, 30 % glycerol and 0.035 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage

Lagerung: -20 °C

Informationen zur Lagerung: Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Haltbarkeit: 24 months

Referenzen für anti-Retinoic Acid Receptor beta Antikörper (ABIN2668691)

Boehm, Samama, Cribier, Rochette-Egly: "Retinoic-acid receptor beta expression in melanocytes." in: European journal of dermatology : EJD, Vol. 14, Issue 1, pp. 19-23, (2004) (PubMed).

Chakravarti, Mathur, Bahadur, Shukla, Rochette-Egly, Ralhan: "Expression of RARalpha and RARbeta in human oral potentially malignant and neoplastic lesions." in: International journal of cancer. Journal international du cancer, Vol. 91, Issue 1, pp. 27-31, (2001) (PubMed).

Details zu Retinoic Acid Receptor beta

Target: Retinoic Acid Receptor beta (RARB) (Retinoic Acid Receptor, beta (RARB))

Andere Bezeichnung: RAR-beta

Hintergrund: RAR-b (HAP, NR1B2) is a member of the thyroid-steroid hormone receptor superfamily of nuclear transcriptional regulators. RAR-b localizes to the cytoplasm and to subnuclear compartments. RAR-b binds retinoic acid, the biologically active form of vitamin A which mediates cellular signaling in embryonic morphogenesis, cell growth and differentiation. It is thought that RAR-b limits growth of many cell types by regulating gene expression.

Molekulargewicht: 50 kDa

Gen-ID: 5915

NCBI Accession: NP_000956

Pathways: Nuclear Receptor Transcription Pathway, Retinoic Acid Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway