DDIT3 Antikörper

Produktnummer ABIN2668558

Es sind 2+ Publikationen für dieses Produkt verfügbar. Der Maus Monoklonal anti-DDIT3 Antikörper wird verwendet zum Nachweis von DDIT3 in Proben von Maus. Er wurde validiert für WB und IP.

Kurzübersicht für DDIT3 Antikörper (ABIN2668558)

Target: DDIT3 (DNA-Damage-Inducible Transcript 3 (DDIT3))

Reaktivität: Maus

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser DDIT3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP)

Klon: 9C8

Produktdetails anti-DDIT3 Antikörper

Verwendungszweck: Ddit3 antibody (mAb) (Clone 9C8)

Aufreinigung: Protein G Chromatography

Immunogen: This antibody was raised against full-length recombinant mouse Ddit3 protein.

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 μg/μL

Buffer: Purified IgG in PBS with 30 % glycerol and 0.035 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage

Lagerung: -20 °C

Informationen zur Lagerung: Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Haltbarkeit: 24 months

Referenzen für anti-DDIT3 Antikörper (ABIN2668558)

Kuroda, Wang, Sok, Yin, Chung, Giannotti, Jacobs, Fitz, Murtha-Riel, Turner, Ron: "Induction of a secreted protein by the myxoid liposarcoma oncogene." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 96, Issue 9, pp. 5025-30, (1999) (PubMed).

Wang, Kuroda, Sok, Batchvarova, Kimmel, Chung, Zinszner, Ron: "Identification of novel stress-induced genes downstream of chop." in: The EMBO journal, Vol. 17, Issue 13, pp. 3619-30, (1998) (PubMed).

Details zu DDIT3

Target: DDIT3 (DNA-Damage-Inducible Transcript 3 (DDIT3))

Andere Bezeichnung: Ddit3

Hintergrund: Ddit3 (DNA-damage-inducible transcript 3, CHOP) is a member of the CCAAT/enhancer-binding protein (C/EBP) family of transcription factors. The protein functions as a dominant-negative inhibitor by forming heterodimers with other C/EBP members, such as C/EBP and LAP (liver activator protein), and preventing their DNA binding activity. The protein is implicated in adipogenesis and erythropoiesis, is activated by endoplasmic reticulum stress, and promotes apoptosis.

Molekulargewicht: 29 kDa

Gen-ID: 13198

NCBI Accession: NP_031863

Pathways: Regulation of Muscle Cell Differentiation, ER-Nucleus Signaling, Skeletal Muscle Fiber Development, Cell RedoxHomeostasis