Histone 3 Antikörper (H3K4me2)

Produktnummer ABIN2668425

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch Histone 3 in WB, ChIP, DB und ChIP-seq. Er zeigt eine Reaktivität gegenüber Human und Maus und wurde in 15+ Publikationen erwähnt.

Kurzübersicht für Histone 3 Antikörper (H3K4me2) (ABIN2668425)

Target: Histone 3 (H3) (Histone H3 (H3))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Histone 3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Chromatin Immunoprecipitation (ChIP), Dot Blot (DB), ChIP DNA-Sequencing (ChIP-seq)

Produktdetails anti-Histone 3 Antikörper

Bindungsspezifität: H3K4me2

Aufreinigung: None

Immunogen: This Histone H3 dimethylLys4 antibody was raised against a peptide including dimethyllysine 4 of histone H3.

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung:

Avoid repeated freeze/thaw cycles and keep on ice when not in storage.

Lagerung: -20 °C

Informationen zur Lagerung: Antibodies in solution can be stored at -20 °C for 2 years.

Haltbarkeit: 6 months

Referenzen für anti-Histone 3 Antikörper (ABIN2668425)

Dheekollu, Wiedmer, Sentana-Lledo, Cassel, Messick, Lieberman: "HCF1 and OCT2 Cooperate with EBNA1 To Enhance OriP-Dependent Transcription and Episome Maintenance of Latent Epstein-Barr Virus." in: Journal of virology, Vol. 90, Issue 11, pp. 5353-67, (2016) (PubMed).

Zhan, Kost-Alimova, Shi, Leo, Bardenhagen, Shepard, Appikonda, Vangamudi, Zhao, Tieu, Jiang, Heffernan, Marszalek, Toniatti, Draetta, Tyler, Barton, Jones, Palmer, Geck Do, Andersen: "Development of novel cellular histone-binding and chromatin-displacement assays for bromodomain drug discovery." in: Epigenetics & chromatin, Vol. 8, pp. 37, (2015) (PubMed).

Mohan, Dialynas, Weake, Liu, Martin-Brown, Florens, Washburn, Workman, Abmayr: "Loss of Drosophila Ataxin-7, a SAGA subunit, reduces H2B ubiquitination and leads to neural and retinal degeneration." in: Genes & development, Vol. 28, Issue 3, pp. 259-72, (2014) (PubMed).

Walter, Matter, Fahrenkrog: "Loss of histone H3 methylation at lysine 4 triggers apoptosis in Saccharomyces cerevisiae." in: PLoS genetics, Vol. 10, Issue 1, pp. e1004095, (2014) (PubMed).

Konovalov, Garcia-Bassets: "Analysis of the levels of lysine-specific demethylase 1 (LSD1) mRNA in human ovarian tumors and the effects of chemical LSD1 inhibitors in ovarian cancer cell lines." in: Journal of ovarian research, Vol. 6, Issue 1, pp. 75, (2014) (PubMed).

Rafehi, Balcerczyk, Lunke, Kaspi, Ziemann, Kn, Okabe, Khurana, Ooi, Khan, Du, Chang, Haviv, Keating, Karagiannis, El-Osta: "Vascular histone deacetylation by pharmacological HDAC inhibition." in: Genome research, Vol. 24, Issue 8, pp. 1271-84, (2014) (PubMed).

Kallestad, Woods, Christensen, Gefroh, Balakrishnan, Milavetz: "Transcription and replication result in distinct epigenetic marks following repression of early gene expression." in: Frontiers in genetics, Vol. 4, pp. 140, (2013) (PubMed).

Cannuyer, Loriot, Parvizi, De Smet: "Epigenetic hierarchy within the MAGEA1 cancer-germline gene: promoter DNA methylation dictates local histone modifications." in: PLoS ONE, Vol. 8, Issue 3, pp. e58743, (2013) (PubMed).

Cie?lik, Hoang, Baranova, Chodaparambil, Kumar, Allison, Xu, Wamsley, Gray, Jones, Mayo, Bekiranov: "Epigenetic coordination of signaling pathways during the epithelial-mesenchymal transition." in: Epigenetics & chromatin, Vol. 6, Issue 1, pp. 28, (2013) (PubMed).

Jamieson, Rountree, Lewis, Stajich, Selker: "Regional control of histone H3 lysine 27 methylation in Neurospora." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 110, Issue 15, pp. 6027-32, (2013) (PubMed).

Subrahmanyam, Du, Ivanova, Chakraborty, Ji, Zhang, Alt, Schatz, Sen: "Localized epigenetic changes induced by DH recombination restricts recombinase to DJH junctions." in: Nature immunology, Vol. 13, Issue 12, pp. 1205-12, (2012) (PubMed).

Milavetz, Kallestad, Gefroh, Adams, Woods, Balakrishnan: "Virion-mediated transfer of SV40 epigenetic information." in: Epigenetics, Vol. 7, Issue 6, pp. 528-34, (2012) (PubMed).

Liang, He, Zhang: "Kdm2b promotes induced pluripotent stem cell generation by facilitating gene activation early in reprogramming." in: Nature cell biology, Vol. 14, Issue 5, pp. 457-66, (2012) (PubMed).

Chandrasekharan, Huang, Chen, Sun: "Histone H2B C-terminal helix mediates trans-histone H3K4 methylation independent of H2B ubiquitination." in: Molecular and cellular biology, Vol. 30, Issue 13, pp. 3216-32, (2010) (PubMed).

Honda, Selker: "Direct interaction between DNA methyltransferase DIM-2 and HP1 is required for DNA methylation in Neurospora crassa." in: Molecular and cellular biology, Vol. 28, Issue 19, pp. 6044-55, (2008) (PubMed).

Details zu Histone 3

Target: Histone 3 (H3) (Histone H3 (H3))

Andere Bezeichnung: Histone H3

Molekulargewicht: 17 kDa

Gen-ID: 3020