ATAD2 Antikörper (C-Term)

Produktnummer ABIN2668366

Der Kaninchen Polyklonal anti-ATAD2 Antikörper wird verwendet zum Nachweis von ATAD2 in Proben von Human. Er wurde validiert für WB und IP.

Kurzübersicht für ATAD2 Antikörper (C-Term) (ABIN2668366)

Target: ATAD2 (ATPase Family, AAA Domain Containing 2 (ATAD2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ATAD2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP)

Produktdetails anti-ATAD2 Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: ATAD2 antibody (pAb)

Aufreinigung: Affinity Purified

Immunogen: This antibody was raised against a peptide within the C-terminal region of human ATAD2.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IP: 5 - 10 µL per IP WB*: 1:500 - 1:2,000 dilution The addition of 0.05 % Tween 20 in the blocking buffer and primary antibody incubation buffer is recommended to aid in detection by Western blot. Individual optimization may be required. *Note: many chromatin-bound proteins are not soluble in a low salt nuclear extract and fractionate to the pellet. Therefore, we recommend a High Salt / Sonication Protocol when preparing nuclear extracts for Western blot.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified IgG in PBS with 30 % glycerol and 0.035 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage

Lagerung: -20 °C

Informationen zur Lagerung: Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Haltbarkeit: 24 months

Details zu ATAD2

Target: ATAD2 (ATPase Family, AAA Domain Containing 2 (ATAD2))

Andere Bezeichnung: ATAD2

Hintergrund: ATAD2 (ATPase family AAA domain-containing protein 2) may be a transcriptional coactivator of the nuclear receptor ESR1 required to induce the expression of a subset of estradiol target genes, such as CCND1, MYC and E2F1. May play a role in the recruitment or occupancy of CREBBP at some ESR1 target gene promoters. May be required for histone hyperacetylation. Involved in the estrogen-induced cell proliferation and cell cycle progression of breast cancer cells.

Molekulargewicht: 160 kDa

Gen-ID: 29028

NCBI Accession: NP_054828