SND1 Antikörper

Produktnummer ABIN2668261

Es sind 2+ Publikationen für dieses Produkt verfügbar. Der Maus Monoklonal anti-SND1 Antikörper wird verwendet zum Nachweis von SND1 in Proben von Human und Maus. Er wurde validiert für WB, IHC, IF, IP und ICC.

Kurzübersicht für SND1 Antikörper (ABIN2668261)

Target: SND1 (Staphylococcal Nuclease Domain Containing Protein 1 (SND1))

Reaktivität: Human, Maus

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser SND1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP), Immunocytochemistry (ICC)

Klon: SN4-1

Produktdetails anti-SND1 Antikörper

Verwendungszweck: SND1 antibody (mAb) (Clone SN4-1)

Aufreinigung: Protein A Chromatography

Immunogen: This antibody was raised against a recombinant protein corresponding to amino acids 505 - 674 of human SND1.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 μg/μL

Buffer: Purified IgG in PBS with 30 % glycerol and 0.035 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage

Lagerung: -20 °C

Informationen zur Lagerung: Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Haltbarkeit: 24 months

Referenzen für anti-SND1 Antikörper (ABIN2668261)

Fashe, Saarikettu, Isomäki, Yang, Silvennoinen: "Expression analysis of Tudor-SN protein in mouse tissues." in: Tissue & cell, Vol. 45, Issue 1, pp. 21-31, (2013) (PubMed).

Saarikettu, Ovod, Vuoksio, Grönholm, Yang, Silvennoinen: "Monoclonal antibodies against human Tudor-SN." in: Hybridoma (2005), Vol. 29, Issue 3, pp. 231-6, (2010) (PubMed).

Details zu SND1

Target: SND1 (Staphylococcal Nuclease Domain Containing Protein 1 (SND1))

Andere Bezeichnung: SND1

Hintergrund: SND1 (staphylococcal nuclease and tudor domain containing 1) functions as a transcriptional coactivator and a modulator of RNA metabolism. As a transcriptional coactivator, it acts as a bridging factor between STAT6 and the basal transcription factors, plays a role in PIM1 regulation of MYB activity and is a transcriptional coactivator for the Epstein-Barr virus nuclear antigen 2 (EBNA2). SND-1 has been identified as part of the RISC complex (RNA-induced silencing complex) and interacts with Ago-2. It is involved in the degradation of hyper-edited inosine containing microRNA precursors as part of the RNA interference pathway.

Molekulargewicht: 115 kDa

Gen-ID: 27044

NCBI Accession: NP_055205