BRD3 Antikörper (C-Term)

Produktnummer ABIN2668232

Zitiert in 1 Publikation. Der Kaninchen Polyklonal anti-BRD3 Antikörper (ABIN2668232) detektiert spezifisch BRD3 in WB, ChIP-seq, ChIP und CUT&RUN. Dieser Antikörper reagiert spezifisch mit Proben aus Human und Maus.

Kurzübersicht für BRD3 Antikörper (C-Term) (ABIN2668232)

Target: BRD3 (Bromodomain Containing 3 (BRD3))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BRD3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ChIP DNA-Sequencing (ChIP-seq), Chromatin Immunoprecipitation (ChIP), Cleavage Under Targets and Release Using Nuclease (CUT&RUN)

Produktdetails anti-BRD3 Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: BRD3 antibody (pAb)

Aufreinigung: Affinity Purified

Immunogen: This antibody was raised against a peptide within the C-terminal region of mouse BRD3.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ChIP: 10 µL per ChIP ChIP-Seq & ChIP-chip: 10 µL each WB: 1:500- 1:2,000 dilution CUT&RUN: 1 µL per 50 µL reaction

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified IgG in PBS with 30 % glycerol and 0.035 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage

Lagerung: -20 °C

Informationen zur Lagerung: Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Haltbarkeit: 24 months

Referenzen für anti-BRD3 Antikörper (ABIN2668232)

Sartor, Powell, Brothers, Wahlestedt: "Epigenetic Readers of Lysine Acetylation Regulate Cocaine-Induced Plasticity." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 35, Issue 45, pp. 15062-72, (2015) (PubMed).

Details zu BRD3

Target: BRD3 (Bromodomain Containing 3 (BRD3))

Andere Bezeichnung: BRD3

Hintergrund: BRD3 (Bromodomain Containing 3) is a member of the mammalian BET (Bromodomain Extra Terminal) family of proteins, binds hyperacetylated chromatin and has been reported to interact with acetylated Histone H4K5, Histone H4K12 and Histone H3K14. It plays a role in the regulation of transcription, probably by chromatin remodeling and interaction with transcription factors. Regulates transcription by promoting the binding of the transcription factor GATA1 to its targets (By similarity). Regulates transcription of the CCND1 gene.

Molekulargewicht: 100 kDa

Gen-ID: 67382

NCBI Accession: NP_001107046

Pathways: Chromatin Binding