CD8 Antikörper (PE)

Produktnummer ABIN2667341

Dieses Anti-CD8-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von CD8 in FACS. Geeignet für Marmoset.

Kurzübersicht für CD8 Antikörper (PE) (ABIN2667341)

Target: CD8

Reaktivität: Marmoset

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD8 Antikörper ist konjugiert mit PE

Applikation: Flow Cytometry (FACS)

Klon: 6F10

Produktdetails anti-CD8 Antikörper (PE)

Kreuzreaktivität: Squirrel Monkey (Saimiri spec.)

Aufreinigung: The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.2 mg/mL

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Protect from prolonged exposure to light. Do not freeze.

Lagerung: 4 °C

Informationen zur Lagerung: The antibody solution should be stored undiluted between 2°C and 8°C.

Details zu CD8

Target: CD8

Andere Bezeichnung: CD8

Hintergrund: CD8a is a 32-34 kD type I glycoprotein. It forms a homodimer (CD8a/a) or heterodimer (CD8a/b) with CD8b. CD8, also known as T8 and Leu2, is a member of the immunoglobulin superfamily found on the majority of thymocytes, a subset of peripheral blood T cells, and NK cells (which express almost exclusively CD8a homodimers). CD8 acts as a co-receptor with MHC class I-restricted T cell receptors in antigen recognition and T cell activation and has been shown to play a role in thymic differentiation. Two domains in CD8a are important for function: the extracellular IgSF domain binds the α3 domain of MHC class I and the cytoplasmic CXCP motif binds the tyrosine kinase p56 Lck.