L-Selectin Antikörper (Alexa Fluor 700)

Produktnummer ABIN2666426

Dieses Anti-L-Selectin-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von L-Selectin in FACS. Geeignet für Chemical.

Kurzübersicht für L-Selectin Antikörper (Alexa Fluor 700) (ABIN2666426)

Target: L-Selectin (SELL) (Selectin L (SELL))

Reaktivität: Chemical

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser L-Selectin Antikörper ist konjugiert mit Alexa Fluor 700

Applikation: Flow Cytometry (FACS)

Klon: DREG-56

Produktdetails anti-L-Selectin Antikörper (Alexa Fluor 700)

Kreuzreaktivität: Schimpanse, Rind (Kuh)

Aufreinigung: The antibody was purified by affinity chromatography, and conjugated with Alexa Fluor® 700 under optimal conditions.

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Details zu L-Selectin

Target: L-Selectin (SELL) (Selectin L (SELL))

Andere Bezeichnung: CD62L

Substanzklasse: Chemical

Hintergrund: CD62L is a 74-95 kD single chain type I glycoprotein referred to as L-selectin or LECAM-1. It is expressed on most peripheral blood B cells, subsets of T and NK cells, monocytes, granulocytes, and certain hematopoietic malignant cells. CD62L binds to carbohydrates present on certain glycoforms of CD34, glycam-1, and MAdCAM-1 and with a low affinity to anionic oligosaccharide sequences related to sialylated Lewis X (sLex, CD15s) through its C-type lectin domain. CD62L is important for the homing of naive lymphocytes to high endothelial venules in peripheral lymph nodes and Peyer's patches. It also plays a role in leukocyte rolling on activated endothelial cells.