NCR1 Antikörper (Alexa Fluor 647)

Produktnummer ABIN2666424

Produktdetails anti-NCR1 Antikörper (Alexa Fluor 647)

Target: NCR1 (Natural Cytotoxicity Triggering Receptor 1 (NCR1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser NCR1 Antikörper ist konjugiert mit Alexa Fluor 647

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Functional Studies (Func), Neutralization (Neut)

Aufreinigung: The antibody was purified by affinity chromatography, and conjugated with Alexa Fluor® 647 under optimal conditions.

Klon: 9E2

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Details zu NCR1

Target: NCR1 (Natural Cytotoxicity Triggering Receptor 1 (NCR1))

Andere Bezeichnung: CD335 (NCR1 Produkte)

Synonyme: CD335 antikoerper, LY94 antikoerper, NK-p46 antikoerper, NKP46 antikoerper, Ly94 antikoerper, NKp46 antikoerper, KILR-1 antikoerper, Nk-p46 antikoerper, Nkp46 antikoerper, natural cytotoxicity triggering receptor 1 antikoerper, NCR1 antikoerper, Ncr1 antikoerper

Hintergrund: CD335, also known as NKp46, is a member of the natural cytotoxicity receptor (NCR) family which triggers cytotoxicity in NK cells. CD335 is direct-ly involved in target cell recognition and lysis, and is exclusively expressed on CD3-CD56+ NK cells, suggesting it is a universal marker for NK cells. NKp46, along with NKp30 and NKp44, is referred to as a natural cytoxicity receptor (NCR) and plays a very important role in killing virus-infected tumor cells and MHC-class I-unprotected cells.

Pathways: Regulation of Leukocyte Mediated Immunity