NCR1 Antikörper (Alexa Fluor 647)

Produktnummer ABIN2666424

Dieser Maus Monoklonal Antikörper detektiert spezifisch NCR1 in WB, ELISA, IHC, Func und Neut. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für NCR1 Antikörper (Alexa Fluor 647) (ABIN2666424)

Target: NCR1 (Natural Cytotoxicity Triggering Receptor 1 (NCR1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser NCR1 Antikörper ist konjugiert mit Alexa Fluor 647

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Functional Studies (Func), Neutralization (Neut)

Klon: 9E2

Produktdetails anti-NCR1 Antikörper (Alexa Fluor 647)

Aufreinigung: The antibody was purified by affinity chromatography, and conjugated with Alexa Fluor® 647 under optimal conditions.

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Details zu NCR1

Target: NCR1 (Natural Cytotoxicity Triggering Receptor 1 (NCR1))

Andere Bezeichnung: CD335

Hintergrund: CD335, also known as NKp46, is a member of the natural cytotoxicity receptor (NCR) family which triggers cytotoxicity in NK cells. CD335 is direct-ly involved in target cell recognition and lysis, and is exclusively expressed on CD3-CD56+ NK cells, suggesting it is a universal marker for NK cells. NKp46, along with NKp30 and NKp44, is referred to as a natural cytoxicity receptor (NCR) and plays a very important role in killing virus-infected tumor cells and MHC-class I-unprotected cells.

Pathways: Regulation of Leukocyte Mediated Immunity