VEGF Antikörper

Produktnummer ABIN2666384

Dieses Anti-VEGF-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von VEGF in BCA. Geeignet für Human.

Kurzübersicht für VEGF Antikörper (ABIN2666384)

Target: VEGF (Vascular Endothelial Growth Factor (VEGF))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser VEGF Antikörper ist unkonjugiert

Applikation: Biochemical Assay (BCA)

Klon: Poly6275

Produktdetails anti-VEGF Antikörper

Aufreinigung: The antibody was purified by antigen-affinity chromatography.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % gelatin.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Upon receipt, store undiluted between 2°C and 8°C.

Details zu VEGF

Target: VEGF (Vascular Endothelial Growth Factor (VEGF))

Andere Bezeichnung: VEGF

Hintergrund: VEGF, also known as vascular endothelial growth factor, vasculotropin, and vascular permeability factor, is a widely expressed mitogen for vascular endothelial cells that has been shown to promote angiogenesis and increase permeability of capillary blood vessels. VEGF is a member of the platelet-derived growth factor (PDGF) family and is produced as a homodimeric protein with approximate molecular weights of 34-46 kD. The variance in molecular weight is a result of alternative splicing events that encode monomeric proteins having 121, 165, 189 or 206 amino acids. VEGF121 and VEGF165 are secreted proteins whereas VEGF189 and VEGF206 are strongly cell-associated. VEGF binds to VEGF-R1 (also known as Flt-1) and VEGF-R2 (also known as KDR). Inhibition of VEGF biding to VEGF-Rs has been the focus of a number of tumor therapeutic strategies. The Poly6275 antibody recognizes the N-terminal region of human VEGF has been shown to be useful for Western blotting of both reduced and non-reduced VEGF.