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IL-33 Antikörper (Ser109)

IL33 Reaktivität: Maus, Ratte WB, IHC, IP, IF Wirt: Ziege Polyclonal Poly5165 unconjugated
Produktnummer ABIN2665498
  • Target Alle IL-33 (IL33) Antikörper anzeigen
    IL-33 (IL33) (Interleukin 33 (IL33))
    Bindungsspezifität
    • 20
    • 16
    • 10
    • 9
    • 6
    • 5
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Ser109
    Reaktivität
    • 83
    • 47
    • 38
    • 9
    • 1
    Maus, Ratte
    Wirt
    • 103
    • 26
    • 7
    • 3
    • 2
    • 1
    • 1
    Ziege
    Klonalität
    • 114
    • 29
    Polyklonal
    Konjugat
    • 71
    • 23
    • 13
    • 7
    • 5
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser IL-33 Antikörper ist unkonjugiert
    Applikation
    • 84
    • 68
    • 36
    • 28
    • 18
    • 15
    • 14
    • 14
    • 11
    • 10
    • 9
    • 5
    • 5
    • 5
    • 4
    • 4
    • 4
    • 3
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunofluorescence (IF)
    Kreuzreaktivität
    Ratte (Rattus)
    Aufreinigung
    The antibody was purified by antigen affinity chromatography.
    Immunogen
    Ser109-Isoleucin266 (Accession# NM_133775) was expressed in E. coli.
    Klon
    Poly5165
    Isotyp
    Ig Fraction, IgG
    Top Product
    Discover our top product IL33 Primärantikörper
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    0.5 mg/mL
    Buffer
    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Do not freeze.
    Lagerung
    4 °C
    Informationen zur Lagerung
    The antibody solution should be stored undiluted between 2°C and 8°C.
  • Target
    IL-33 (IL33) (Interleukin 33 (IL33))
    Andere Bezeichnung
    IL-33 (IL33 Produkte)
    Synonyme
    IL33 antikoerper, C9orf26 antikoerper, DVS27 antikoerper, IL1F11 antikoerper, NF-HEV antikoerper, NFEHEV antikoerper, RP11-575C20.2 antikoerper, 9230117N10Rik antikoerper, Il-33 antikoerper, Il1f11 antikoerper, RGD1311155 antikoerper, interleukin 33 antikoerper, IL33 antikoerper, Il33 antikoerper
    Hintergrund
    IL-33 belongs to the IL-1 family and is closely related in structure to IL-18 and IL-1b. IL-33, IL-1b, and IL-18 are synthesized as biologically inactive precursor and are cleaved by the enzyme caspase-1 to be secreted as active mature forms. IL-33 stimulates target cells by binding to the IL-1R/TLR superfamily member ST2 and subsequently activates NF-κB and MAPK pathways via identical signalling events to those observed for IL-1b. In addition, IL-33 is a nuclear factor (NF-HEV) abundantly expressed in high endothelial venules from lymphoid organs that associates with chromatin and exhibits transcriptional regulatory properties.
    Pathways
    Production of Molecular Mediator of Immune Response
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