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IL-33 Antikörper (Ser109)
IL33
Reaktivität: Maus, Ratte
WB, IHC, IP, IF
Wirt: Ziege
Polyclonal
Poly5165
unconjugated
Produktnummer ABIN2665498
Produktdetails anti-IL-33 Antikörper
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Target
Alle IL-33 (IL33) Antikörper anzeigen
IL-33 (IL33)
(Interleukin 33 (IL33))
Bindungsspezifität
Alle Epitope für IL-33 Antikörper
Ser109
Reaktivität
Alle Reaktivitäten für IL-33 Antikörper
Maus, Ratte
Wirt
Alle Wirte für IL-33 Antikörper
Ziege
Klonalität
Alle Klonalitäten für IL-33 Antikörper
Polyklonal
Konjugat
Alle Konjugate für IL-33 Antikörper
Dieser IL-33 Antikörper ist unkonjugiert
Applikation
Alle Applikationen für IL-33 Antikörper
Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunofluorescence (IF)
Kreuzreaktivität
Ratte (Rattus)
Aufreinigung
The antibody was purified by antigen affinity chromatography.
Immunogen
Ser109-Isoleucin266 (Accession# NM_133775) was expressed in E. coli.
Klon
Poly5165
Isotyp
Ig Fraction, IgG
Top Product
Discover our top product IL33 Primärantikörper
Alternativen
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Anwendungsinformationen
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Applikationshinweise
Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Konzentration
0.5 mg/mL
Buffer
Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung
Do not freeze.
Lagerung
4 °C
Informationen zur Lagerung
The antibody solution should be stored undiluted between 2°C and 8°C.
Details zu IL-33
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Target
IL-33 (IL33)
(Interleukin 33 (IL33))
Andere Bezeichnung
IL-33 (IL33 Produkte )
Synonyme
IL33 antikoerper, C9orf26 antikoerper, DVS27 antikoerper, IL1F11 antikoerper, NF-HEV antikoerper, NFEHEV antikoerper, RP11-575C20.2 antikoerper, 9230117N10Rik antikoerper, Il-33 antikoerper, Il1f11 antikoerper, RGD1311155 antikoerper, interleukin 33 antikoerper, IL33 antikoerper, Il33 antikoerper
Hintergrund
IL-33 belongs to the IL-1 family and is closely related in structure to IL-18 and IL-1b. IL-33, IL-1b, and IL-18 are synthesized as biologically inactive precursor and are cleaved by the enzyme caspase-1 to be secreted as active mature forms. IL-33 stimulates target cells by binding to the IL-1R/TLR superfamily member ST2 and subsequently activates NF-κB and MAPK pathways via identical signalling events to those observed for IL-1b. In addition, IL-33 is a nuclear factor (NF-HEV) abundantly expressed in high endothelial venules from lymphoid organs that associates with chromatin and exhibits transcriptional regulatory properties.
Pathways
Production of Molecular Mediator of Immune Response
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