TCR V Gamma1.1 + V Gamma1.2 Antikörper

Produktnummer ABIN2665404

Produktdetails

Target: TCR V Gamma1.1 + V Gamma1.2

Reaktivität: Maus

Wirt: Armenischer Hamster

Klonalität: Monoklonal

Konjugat: Unkonjugiert

Applikation: Intracellular Flow Cytometry (ICFC)

Aufreinigung: The antibody was purified by affinity chromatography.

Klon: 4B2-9

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: The antibody solution should be stored undiluted between 2°C and 8°C.

Antigendetails

Target: TCR V Gamma1.1 + V Gamma1.2

Hintergrund: In mice, the TCR g locus consists of seven Vg, four Jg and four Cg genes, which are differentially expressed through their lifespan. During fetal and early postnatal life, very few γ/δ T cells express TCR Vγ1.1 or Vγ 1.2 chains. In adult mice, however, a major fraction of the γ/δ T cell repertoire comprise either TCR Vγ1.1 or Vγ1.2 chains. The Vγ1.1 gene rearranges almost exclusively with the Jg4-Cg4 genes, while the Vγ1.2 gene preferentially does with Jg1.