TCR V Beta8.1 Antikörper
Kurzübersicht für TCR V Beta8.1 Antikörper (ABIN2665400)
Target
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Aufreinigung
- The antibody was purified by affinity chromatography.
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Isotyp
- IgG2a kappa
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anti-TCR V Beta8.1 antibody (FITC)
Reaktivität: Maus WB, ELISA (Capture), ELISPOT (Capture), Neut Wirt: Ratte Monoclonal KJ16-133-18 FITC
anti-TCR V Beta8.1 antibody (PE)Reaktivität: Maus FACS, IHC Wirt: Ratte Monoclonal KJ16-133-18 PE
anti-TCR V Beta8.1 antibody (PE)Reaktivität: Maus ELISA (Detection) Wirt: Maus Monoclonal MR5-2 PE
anti-TCR V Beta8.1 antibodyReaktivität: Maus WB, IF Wirt: Maus Monoclonal MR5-2 unconjugated
anti-TCR V Beta8.1 antibody (Alexa Fluor 647)Reaktivität: Maus FACS Wirt: Ratte Monoclonal KJ16-133-18 Alexa Fluor 647
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 0.5 mg/mL
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Buffer
- Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Informationen zur Lagerung
- The antibody solution should be stored undiluted between 2°C and 8°C.
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- TCR V Beta8.1
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Hintergrund
- The TCR Vβ 8 family consists of three members, namely Vβ8.1, 8.2 and 8.3. KJ16-133.18 reacts with Vβ8.1, 8.2 only, but not Vβ8.3. Most mouse strains have about 20 % Vβ 8+ T cells in the periphery.However, C57BR, C57L, SJL, SWR (Tcra haplotype) and RIII strains (Tcrc haplotype) do not express Vβ8 due to a gene deletion at the Vβ 8 family loci.Other strains expressing endogenous super-antigen, such as Mls-1a have significant reduced number of Vβ 8.1 cells in the periphery.Exogenous superantigen, such as staphylococcal enterotoxin B, stimulates lymphocytes bearing Vβ 8 and selectively eliminate those T cells in vivo.
Target
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