PAX9 Antikörper

Produktnummer ABIN2665320

Produktdetails anti-PAX9 Antikörper

Target: PAX9 (Paired Box 9 (PAX9))

Reaktivität: Human, Maus

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser PAX9 Antikörper ist unkonjugiert

Applikation: Multiplex Assay (MA)

Aufreinigung: The antibody was purified by affinity chromatography.

Klon: 14D10A24

Isotyp: IgG2a kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: The antibody solution should be stored undiluted between 2°C and 8°C.

Details zu PAX9

Target: PAX9 (Paired Box 9 (PAX9))

Andere Bezeichnung: PAX9 (PAX9 Produkte)

Synonyme: STHAG3 antikoerper, ChPax9 antikoerper, PAX-9 antikoerper, Pax-9 antikoerper, xpax9 antikoerper, xpax-9 antikoerper, paired box 9 antikoerper, paired box 9 L homeolog antikoerper, PAX9 antikoerper, pax9 antikoerper, Pax9 antikoerper, pax9.L antikoerper

Hintergrund: PAX9 is a transcription factor belonging to the PAX family, which is composed of nine members defined by the presence of a paired box domain responsible for DNA binding. PAX9 is expressed at the E10 stage and downregulated at the bell stage. It is controlled by Fgf/Bmp signaling and plays an essential role in tooth development. PAX9 deficient mice fail to form teeth and show developmental arrest at the bud stage. In humans, heterozygous mutation in PAX9 is associate with tooth agenesis. These findings support the role of PAX9 in tooth development.