IL23 Antikörper
Kurzübersicht für IL23 Antikörper (ABIN2665147)
Target
Alle IL23 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Aufreinigung
- The antibody was purified by affinity chromatography.
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Isotyp
- IgG2b kappa
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anti-Interleukin 23 (IL23) (AA 101-196) antibody
IL23 Reaktivität: Human, Ratte WB, ELISA, IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-Interleukin 23 (IL23) (C-Term) antibodyIL23 Reaktivität: Human, Maus WB, IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-Interleukin 23 (IL23) antibodyIL23 Reaktivität: Human IHC, ELISA, Func Wirt: Maus Monoclonal B-Z23 unconjugated
anti-Interleukin 23 (IL23) (C-Term) antibodyIL23 Reaktivität: Human, Maus WB, ELISA, ICC Wirt: Kaninchen Polyclonal unconjugated
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 0.5 mg/mL
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Buffer
- Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Informationen zur Lagerung
- The antibody solution should be stored undiluted between 2°C and 8°C.
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- IL23 (Interleukin 23 (IL23))
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Andere Bezeichnung
- IL-23
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Hintergrund
- Interleukin 23 (IL-23) is a heterodimeric cytokine composed of two disulfide-linked subunits, a p19 subunit that is unique to IL-23, and a p40 subunit that is shared with IL-12.IL-23 is secreted by activated macrophages and dendritic cells.Human and mouse p19 share 70 % aa sequence identity. The functional IL-23 receptor complex consists of two receptor subunits, a β1 subunit shared with the IL-12 receptor (IL-12R β1) and a β2-like subunit with STAT4 binding domain, termed the IL-23-specific receptor subunit (IL-23R).IL-23 has been shown to enhance IFN-γ production by memory T cells.Additionally, mouse IL-23 (but not IL-12) can activate mouse memory T cells to produce the potent proinflammatory cytokine IL-17.IL-23 has been shown to be upregulated in certain autoimmune diseases and promote immunity in response to some viral and mycobacterial infections.
Target
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